Results 101 to 110 of about 25,597 (262)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Вестник Тамбовского университета. Серия: Гуманитарные наукиThe study of certain aspects of social adaptation and support, pension coverage and employment of disabled veterans of the Great Patriotic War allows us to clarify the peculiarities of post-war society development, development trajectories of the ...
P. P. Shcherbinin
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Digital war diaries: Witnessing the 2022 Russian War against Ukraine
Memory, Mind & MediaDigital media have changed the ways people mobilise and act collectively in times of crisis. During the Russian aggression against Ukraine, they have been at the forefront of war coverage giving users the possibility to share experiences of wartime ...
Svitlana Kot +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
“Spain is fighting for us”. Representations of the Spanish Civil War by the German left in exil
Diacronie. Studi di Storia Contemporanea, 2011 In this article, the press coverage of the Spanish Civil War by four German exile papers will be studied, raising the questions why the German left in exile was so much concerned with the conflict and how they connected the events in Spain with their own
Claudia Roesch is a junior researcher at the Department of History of University of Münster, Germany, working in the Emmy Noether Research Group “Family Values and Social Change- The US American Family in the 20th Century“ on a project about Mexican immigrant families. She has received her master’s degree at Humboldt-University of Berlin in 2009 with a master thesis: „Spanien kämpft für uns – Die Bedeutung des Spanischen Bürgerkriegs für die deutsche Linke im Exil 1936-1939“ [Spain is fighting for us – the significance of the Spanish Civil War for the German left in exile]. Research interests are studies of modernism, migration and exile history in an Ibero-American realm. URL: < http://www.uni-muenster.de/Geschichte/hist-sem/NwG-ZG/Mitarbeiter/croesch/index.html >
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
“Spectacle of Broken Cities and Broken Lives”
Medien & ZeitThis paper examines how the Spanish Civil War (1936–1939) was portrayed in the United States through innovative media forms. By conducting a qualitative content analysis of news outlets of Time Inc, the study investigates how photography, radio, and ...
Jakob Irler
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