Results 71 to 80 of about 542,970 (299)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Soldiers Past and Future: The Civil War and Great War Meet in Gettysburg
, 2014 Gettysburg, a town already so intimately acquainted with war, was the scene of particularly interesting historical encounters. The still too present memory of the Civil War impacted the way Gettysburgians viewed the Great War.
Johnson, S. Marianne
core
From Stalingrad to Grozny: Patriotism, political pressure, and literature in the war reporting of Vassily Grossman and Anna Politkovskaya [PDF]
, 2014 Comparing the work of the 20th century Soviet journalist and writer, Vassily Grossman, with that of his compatriot, Anna Politkovskaya, almost half a century later, this article examines the two journalists’ writing for what it tells us about the ...
Babel I +16 more
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Canada’s Peacekeepers Remember [PDF]
, 2012 Stopping wars, keeping them from restarting, and observing the implementation of cease-fires—various shades of “peacekeeping”—have always been dangerous work. It has become particularly so over the past decade as peacekeepers increasingly find themselves
Johnston, Murray
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
In the mood for a commercial break? A model of consumer response to television commercials during sensitive news [PDF]
Marketers decided to pull over $100 million worth of commercials from network, cable, local and syndicated TV outlets on the United States market in the first 48 hours of the 2003 Iraq war.
Anca C. MICU +2 more
core
Operation Moshtarak and the manufacture of credible, “heroic” warfare [PDF]
, 2010 Richard Lance Keeble argues that Fleet Street’s coverage of the Afghan conflict has served largely to promote the interests of the military/industrial/media complex – and marginalise the views of the public who have consistently appealed in polls for the
Amoore M +12 more
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source