Results 151 to 160 of about 502,531 (307)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

War on Drugs in the Philippines: Evaluating Fear Appeals as Antidote to Continued Drug Use. [PDF]

Acta Med Philipp
Monsada MDY, Ramiro LS, Martinez AB, Miranda GMJ, Estacio JZD, Alibudbud RC, Estacio LR.   +6 more
europepmc   +1 more source

Post-war prevention: Emerging frameworks to prevent drug use after the War on Drugs. [PDF]

Int J Drug Policy, 2018
Werb D.
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

From (Most) Violent to Resilient City:

Parse Journal
The text describes the process of borderization within the urban reform of Medellín, Colombia. This borderization is located within the context of a transformed discourse of human security deployed in response to the changing dynamics of violence by ...
Lou Barzaghi
doaj  

Neo-colonialism and financing for the war on drugs: a review of current policy and recommendations for countries in the global north. [PDF]

Harm Reduct J
Daniels C, Burke-Shyne N, Cook C, Beattie A.   +3 more
europepmc   +1 more source

On Ending the War on Drugs [PDF]

, 2011
Gaffney, Edward McGlynn, Jr.
core   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Isaac Campos. Home grown: Marijuana and the origins of Mexico's war on drugs. [PDF]

Addiction
Hall W, Yeates S.
europepmc   +1 more source

War on Drugs Policing and Police Brutality. [PDF]

Subst Use Misuse, 2015
Cooper HL.
europepmc   +1 more source