Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Reporting Vietnam. Media and military at war - W. M. Hammond.
Ten Cate, Arthur
doaj +1 more source
Toward a humanized technology: a reinterpretation of Erich Fromm' s humanistic peace psychology. [PDF]
Wang Y, Li P, Liu W.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The effects of war on digital adherence technology engagement for TB treatment in Ukraine. [PDF]
Deyanova N +9 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Cancer care in wartime Ukraine: disruption, resilience and recovery. [PDF]
Karavska A +6 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Exposure to wartime sexual violence in Bosnia and Herzegovina: nationally representative prevalence 30 years after the 1992-1995 war. [PDF]
Schaub M +3 more
europepmc +1 more source
Корпоративний медіа-вплив та аспекти мовного воркшопу (Corporate Media Influence and Aspects of Language Workshop) [PDF]
Штайнгауер, Ренді (Randy Steinhauer)
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