Results 281 to 290 of about 157,233 (338)

Dynamic pH profiles drive higher cell‐specific and volumetric productivity

open access: yesBiotechnology Progress, EarlyView.
Implementation of dyamic pH profiles for increased CHO cell culture productivity. Abstract Mammalian cell cultures in bioreactors rely heavily on critical process parameter control to ensure optimal growth, productivity, and reproducibility to produce recombinant therapeutic proteins. Culture pH has been shown to be a critical parameter that influences
Stephanie R. Klaubert   +6 more
wiley   +1 more source

Lactylation in cancer biology: Unlocking new avenues for research and therapy

open access: yesCancer Communications, EarlyView.
Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou   +6 more
wiley   +1 more source

Tumor-Associated Lactic Acidosis and Early Death in Patients With Lymphoma. [PDF]

open access: yesCancer Med
Atamna B   +7 more
europepmc   +1 more source

Gold‐Dithiocarbamato Glycoconjugates as Potential Anticancer Agents: Design, Physico‐Chemical Characterization, and In Vitro Biological Activity

open access: yesChemBioChem, EarlyView.
Metal‐dithiocarbamato glycoconjugates based on gold(III), gold(I)‐phosphino, and gold(I)‐carbene scaffolds are here investigated as potential anticancer agents. Contrary to expectations, they induce cell death by acting at the extracellular level rather than targeting overexpressed glucose transporters.
Andrea Pettenuzzo   +4 more
wiley   +1 more source

Lactylation in cancer: Advances and opportunities for treatment resistance. [PDF]

open access: yesClin Transl Med
Xu K   +10 more
europepmc   +1 more source

High‐Entropy Engineering of O3‐Type Layered Cathodes for Long‐Cycle Life Sodium‐Ion Batteries

open access: yesChemistryEurope, EarlyView.
The disordered coordination environment in transition metals layer in high‐entropy oxides promotes the charge delocalization, enhancing the structural stability of the material and significantly improving its cycling stability. Sodium‐ion batteries (SIBs) are increasingly regarded as promising alternatives to lithium‐ion batteries (LIBs) due to their ...
Wendi Dong   +5 more
wiley   +1 more source

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