Pharmacological Assessment of the Antiprotozoal Activity, Cytotoxicity and Genotoxicity of Medicinal Plants Used in the Treatment of Malaria in the Greater Mpigi Region in Uganda [PDF]
We investigated the potential antimalarial and toxicological effects of 16 medicinal plants frequently used by traditional healers to treat malaria, fever, and related disorders in the Greater Mpigi region in Uganda. Species studied were Albizia coriaria,
Fabien Schultz +10 more
doaj +2 more sources
Antiinflammatory Medicinal Plants from the Ugandan Greater Mpigi Region Act as Potent Inhibitors in the COX-2/PGH2 Pathway [PDF]
Our study investigates 16 medicinal plants via assessment of inhibition of proinflammatory enzymes such as cyclooxygenases (COX). The plants are used by traditional healers in the Greater Mpigi region in Uganda to treat inflammation and related disorders.
Fabien Schultz +4 more
doaj +2 more sources
Traditional medicine trade and uses in the surveyed medicine markets of Western Kenya. [PDF]
Background: There exist vast traditional medicine and herbal remedies prescribed for diseases and socio-cultural ills that are sold in local medicine markets.Objectives: To assess the common traditional medicine traded in the local medicine markets and ...
Chebii WK, Muthee JK, Kiemo JK.
europepmc +3 more sources
Antimicrobial drimane sesquiterpenes and their effect on endophyte communities in the medical tree Warburgia ugandensis [PDF]
Metabolite profiles (GC–MS), drimane sesquiterpenes, sugars and sugar alcohols, were compared with bacterial and fungal endophyte communities (T-RFLP, DNA clones, qPCR) in leaves and roots of the pepper bark tree, Warburgia ugandensis (Canellaceae).
Sigrid eDrage +5 more
doaj +3 more sources
The genetic legacy of fragmentation and overexploitation in the threatened medicinal African pepper-bark tree, Warburgia salutaris. [PDF]
The pepper-bark tree (Warburgia salutaris) is one of the most highly valued medicinal plant species worldwide. Native to southern Africa, this species has been extensively harvested for the bark, which is widely used in traditional health practices ...
Senkoro AM +7 more
europepmc +4 more sources
Estimation of out-crossing rate in a natural breeding population of Warburgia ugandensis using AFLP marker [PDF]
Warburgia ugandensis Sprague (Canellaceae) occurs in East and Central Africa, and the species is of great medicinal importance to the local communities where it occurs.
Jamnadass, RH +3 more
core +4 more sources
11α-Hydroxy muzigadiolide, a novel drimane sesquiterpene from the stem bark of warburgia ugandensis
The stem bark of Warburgia ugandensis provided a new drimane sesquiterpene 11-hydroxy muzigadiolide whose structure was elucidated on the basis of spectral measurements.
John M. Ndegwa, Mohamed S. Rajab
doaj +3 more sources
Immunostimulatory responses to crude extracts of Warburgia ugandensis (Sprague) subsp ugandensis (Canellaceae) by BALB/c mice infected with Leishmania major. [PDF]
To determine the immunostimulatory potential of crude extracts of Warburgia ugandensis subsp. ugandensis with a soluble leishmanial antigen in vaccinating BALB/c mice.Seventy two female BALB/c mice were randomly assigned into six groups. The mice were vaccinated with soluble leishmania antigens (SLA) alone, hexane, ethyl acetate, and dichloromethane ...
Ngure P +6 more
europepmc +3 more sources
Medicinal Plants Used in the Management of Sexual Dysfunction, Infertility and Improving Virility in the East African Community: A Systematic Review. [PDF]
Sexual disorders such as erectile dysfunction (ED), sterility, and sexual inappetence represent some of the complex reproductive challenges that require addressing the underlying causes. The aim of this paper was to systematically synthesize literature on the ethnobotany, phytochemistry, bioactivities, and safety of plants used as remedies for managing
Kyarimpa C +6 more
europepmc +2 more sources
Safety and Efficacy of Medicinal Plants Used to Manufacture Herbal Products with Regulatory Approval in Uganda: A Cross-Sectional Study. [PDF]
Introduction. The Uganda National Drug Authority requires phytochemical screening, freedom from microbial contamination, and evidence of safety and efficacy of the constituent plants to register herbal products. Since Uganda has no pharmacopeia, safety, efficacy, and plant processing information are not readily available.
Kaggwa B +10 more
europepmc +2 more sources

