Results 281 to 290 of about 210,353 (388)

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, Volume 89, Issue 5, Page 384-397, September 2025.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source

Comparative clinical outcomes of acenocoumarol versus direct oral anticoagulants (DOACs) and warfarin in patients with atrial fibrillation: real-world-evidence (SIESTA-A study). [PDF]

Front Pharmacol
Montero-Balosa MC, Limón-Mora JA, Leal-Atienza A, García-Robredo B, Sánchez-Villegas P, Isabel-Gómez R, Aguado-Romeo MJ, Luque Romero LG, Molina-López MT.   +8 more
europepmc   +1 more source

Extended use of dabigatran, warfarin, or placebo in venous thromboembolism.

New England Journal of Medicine, 2013
S. Schulman, C. Kearon, A. Kakkar, S. Schellong, H. Eriksson, David Baanstra, A. M. Kvamme, J. Friedman, P. Mismetti, S. Goldhaber   +9 more
semanticscholar   +1 more source

Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes

Annals of Human Genetics, Volume 89, Issue 5, Page 398-405, September 2025.
ABSTRACT Pharmacogenomics, the use of germline genomic data to guide prescription to improve effective and safer medication, holds promise as a clinical intervention. To date in most health systems, there has been limited uptake of pharmacogenomic testing confined to a few single drug–gene associations.
John Henry McDermott, Videha Sharma, Jessica Keen, William Gerard Newman   +3 more
wiley   +1 more source

Appropriate target range of INR and predictive factors of recurrent thrombosis and bleeding in patients with venous thromboembolism on warfarin. [PDF]

Sci Rep
Sae-Lim P, Saelue P.
europepmc   +1 more source

Magnetic resonance imaging‐guided transurethral ultrasound ablation for benign prostatic obstruction: 1‐year clinical outcomes of a phase II study

BJU International, Volume 136, Issue 3, Page 473-483, September 2025.
Objectives To evaluate the safety and efficacy of magnetic resonance imaging (MRI)‐guided transurethral ultrasound ablation (TULSA) as a minimally invasive alternative for benign prostatic obstruction (BPO). Patients and Methods This prospective, single‐centre, early phase II study (NCT03350529) included 30 men with BPO scheduled for primary ...
Antti Viitala, Mikael Anttinen, Pietari Mäkelä, Heikki Pärssinen, Pertti Nurminen, Teija Sainio, Jani Saunavaara, Pekka Taimen, Roberto Blanco Sequeiros, Peter J. Boström   +9 more
wiley   +1 more source

Comparative Efficacy and Safety of Direct Oral Anticoagulants Versus Warfarin in Valvular Atrial Fibrillation: A Systematic Qualitative Review. [PDF]

Cureus
Chaudhri M, Al Mahrizi AD, Faltas M, Sakowski L, Rajendran P, Borgmann J, Rapelli V, Jaffri Z, Patel N, La Q, Parikh SA, Acquah F, Kaunzinger C, Mehra A.   +13 more
europepmc   +1 more source

Venous Thromboembolism Prophylaxis After TKA: Aspirin, Warfarin, Enoxaparin, or Factor Xa Inhibitors?

Clinical Orthopaedics and Related Research, 2017
Abiram Bala, J. Huddleston, S. Goodman, W. Maloney, D. Amanatullah   +4 more
semanticscholar   +1 more source

Stroke prevention in atrial fibrillation: A narrative review of current evidence and emerging strategies

European Journal of Clinical Investigation, Volume 55, Issue 9, September 2025.
Effective stroke prevention in AF requires a comprehensive holistic approach incorporating appropriate risk stratification, guideline‐adherent anticoagulation and management of underlying cardiovascular conditions and other comorbidities. The ABC pathway, supported by characterisation using the 4S‐AF framework, provides a structured approach to ...
Amir Askarinejad, Deirdre A. Lane, Parham Sadeghipour, Majid Haghjoo, Gregory Y. H. Lip   +4 more
wiley   +1 more source

Anticoagulation for Stroke Prevention in Patients with Atrial Fibrillation: A Review of the Literature and Current Guidelines. [PDF]

Rev Cardiovasc Med
Vyas V, Vyas V, Sharma A, Ashok Kumar P.
europepmc   +1 more source