Results 311 to 320 of about 162,494 (358)
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Annals of Internal Medicine, 2005
Warfarin or not warfarin? That is the question.Each day, physicians who treat elderly patients, especially octogenar-ians, consider this dilemma. Benefits of warfarin are well known inpatients 75 years of age or older. However, compared with youngerpatients, this group is at higher risk for intracranial hemorrhage andother types of warfarin-associated ...
Daniel E. Singer, Margaret C. Fang
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Warfarin or not warfarin? That is the question.Each day, physicians who treat elderly patients, especially octogenar-ians, consider this dilemma. Benefits of warfarin are well known inpatients 75 years of age or older. However, compared with youngerpatients, this group is at higher risk for intracranial hemorrhage andother types of warfarin-associated ...
Daniel E. Singer, Margaret C. Fang
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Annual Review of Medicine, 2010
Warfarin is a drug with a narrow therapeutic index and a wide interindividual variability in dose requirement. Because it is difficult to predict an accurate dose for an individual, patients starting the drug are at risk of thromboembolism or bleeding associated with underdosing or overdosing, respectively.
Kamali F, Wynne H
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Warfarin is a drug with a narrow therapeutic index and a wide interindividual variability in dose requirement. Because it is difficult to predict an accurate dose for an individual, patients starting the drug are at risk of thromboembolism or bleeding associated with underdosing or overdosing, respectively.
Kamali F, Wynne H
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Warfarin and Warfarin‐Alcohol Levels in Anticoagulated Patients
Australian and New Zealand Journal of Medicine, 1979Summary: The relationship between dosage, prothrombin ratio, and steady‐state plasma concentrations of warfarin and warfarin‐alcohol, were determined in 43 patients regularly attending an anticoagulant clinic.The warfarin and warfarin‐alcohol concentrations were determined by a gas chromatographic mass spectroscopic (GC/MS) method.
A. M. Duffield +4 more
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Archives of Pediatrics & Adolescent Medicine, 1975
A remarkable syndrome of congenital anomalies has been described in recent years, which has been tentatively attributed to maternal consumption of warfarin sodium (Coumadin) throughout pregnancy. One case reported by Kerber et al 1 in 1968 described pregnancy in a patient with a prosthetic valve, associated with a fetal anomaly ascribed by the authors ...
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A remarkable syndrome of congenital anomalies has been described in recent years, which has been tentatively attributed to maternal consumption of warfarin sodium (Coumadin) throughout pregnancy. One case reported by Kerber et al 1 in 1968 described pregnancy in a patient with a prosthetic valve, associated with a fetal anomaly ascribed by the authors ...
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Pharmacogenomics of warfarin: Uncovering a piece of the warfarin mystery
American Journal of Health-System Pharmacy, 2009The literature on the pharmacogenomics of warfarin and the use of genetic testing to optimize initial and maintenance warfarin dosing is reviewed.Warfarin tablets contain a racemic mixture of R- and S-isomers. The S-isomer is responsible for about 70% of warfarin's anticoagulant effect.
Gloria R. Grice +2 more
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Annals of Internal Medicine, 1982
Excerpt To the editor: The information in the recent letter by Krauss (1) is misleading on three counts and calls for a response.
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Excerpt To the editor: The information in the recent letter by Krauss (1) is misleading on three counts and calls for a response.
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Annals of Internal Medicine, 1973
Excerpt To the editor: A recent article by O'Reilly (1) has a misleading statement in the abstract: "An augmentation of the therapeutic effect of a drug by disulfiram has thus been shown for the fi...
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Excerpt To the editor: A recent article by O'Reilly (1) has a misleading statement in the abstract: "An augmentation of the therapeutic effect of a drug by disulfiram has thus been shown for the fi...
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Pharmacodynamics of warfarin in cats
Journal of Veterinary Pharmacology and Therapeutics, 2000The overall purpose of this study was to evaluate the pharmacodynamic response to warfarin in cats. The specific aim was to determine if a log‐linear indirect response model (Nagashima et al., 1969) used to describe the in vivo effect of warfarin in humans could be applied to cats.
Lisa C. Freeman +4 more
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Archives of Family Medicine, 1992
Skin and subcutaneous tissue necrosis is a rare complication of warfarin therapy. Although the incidence is low, with increased use of warfarin family physicians need to be aware of this potentially catastrophic event. This article reviews the history of warfarin necrosis and discusses its clinical presentation.
J T, McKnight +2 more
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Skin and subcutaneous tissue necrosis is a rare complication of warfarin therapy. Although the incidence is low, with increased use of warfarin family physicians need to be aware of this potentially catastrophic event. This article reviews the history of warfarin necrosis and discusses its clinical presentation.
J T, McKnight +2 more
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Pediatric Pathology & Molecular Medicine, 2003
A 34-year-old gravida 2 para 1 (1001) mother was on prophylactic anticoagulation therapy because of pulmonary emboli postabdominal surgery. The pregnancy was terminated at 25 weeks' gestation after ultrasound examination showed a mild hydrocephalus and a cardiac structural defect.
Kiat Yeong, Chan +2 more
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A 34-year-old gravida 2 para 1 (1001) mother was on prophylactic anticoagulation therapy because of pulmonary emboli postabdominal surgery. The pregnancy was terminated at 25 weeks' gestation after ultrasound examination showed a mild hydrocephalus and a cardiac structural defect.
Kiat Yeong, Chan +2 more
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