Results 371 to 380 of about 192,309 (409)

Warfarin or Not Warfarin?

Annals of Internal Medicine, 2005
Warfarin or not warfarin? That is the question.Each day, physicians who treat elderly patients, especially octogenar-ians, consider this dilemma. Benefits of warfarin are well known inpatients 75 years of age or older. However, compared with youngerpatients, this group is at higher risk for intracranial hemorrhage andother types of warfarin-associated ...
Daniel E. Singer, Margaret C. Fang
openaire   +4 more sources

Pharmacogenetics of Warfarin

Annual Review of Medicine, 2010
Warfarin is a drug with a narrow therapeutic index and a wide interindividual variability in dose requirement. Because it is difficult to predict an accurate dose for an individual, patients starting the drug are at risk of thromboembolism or bleeding associated with underdosing or overdosing, respectively.
Farhad Kamali, Hilary Wynne
openaire   +2 more sources

Tinzaparin vs Warfarin for Treatment of Acute Venous Thromboembolism in Patients With Active Cancer: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2015
IMPORTANCE Low-molecular-weight heparin is recommended over warfarin for the treatment of acute venous thromboembolism (VTE) in patients with active cancer largely based on results of a single, large trial. OBJECTIVE To study the efficacy and safety of
Agnes Y Y Lee   +6 more
semanticscholar   +1 more source

Warfarin and Warfarin‐Alcohol Levels in Anticoagulated Patients

Australian and New Zealand Journal of Medicine, 1979
Summary: The relationship between dosage, prothrombin ratio, and steady‐state plasma concentrations of warfarin and warfarin‐alcohol, were determined in 43 patients regularly attending an anticoagulant clinic.The warfarin and warfarin‐alcohol concentrations were determined by a gas chromatographic mass spectroscopic (GC/MS) method.
A. M. Duffield   +4 more
openaire   +3 more sources

A Warfarin Embryopathy?

Archives of Pediatrics & Adolescent Medicine, 1975
A remarkable syndrome of congenital anomalies has been described in recent years, which has been tentatively attributed to maternal consumption of warfarin sodium (Coumadin) throughout pregnancy. One case reported by Kerber et al 1 in 1968 described pregnancy in a patient with a prosthetic valve, associated with a fetal anomaly ascribed by the authors ...
openaire   +3 more sources

Pharmacogenomics of warfarin: Uncovering a piece of the warfarin mystery

American Journal of Health-System Pharmacy, 2009
The literature on the pharmacogenomics of warfarin and the use of genetic testing to optimize initial and maintenance warfarin dosing is reviewed.Warfarin tablets contain a racemic mixture of R- and S-isomers. The S-isomer is responsible for about 70% of warfarin's anticoagulant effect.
Gloria R. Grice   +2 more
openaire   +3 more sources

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