Results 21 to 30 of about 448 (160)

3D In Vitro Human Organ Mimicry Devices for Drug Discovery, Development, and Assessment

Advances in Polymer Technology, Volume 2020, Issue 1, 2020., 2020
The past few decades have shown significant advancement as complex in vitro humanized systems have substituted animal trials and 2D in vitro studies. 3D humanized platforms mimic the organs of interest with their stimulations (physical, electrical, chemical, and mechanical).
Aida Rodriguez-Garcia, Jacqueline Oliva-Ramirez, Claudia Bautista-Flores, Samira Hosseini, Mona Semsarilar   +4 more
wiley   +1 more source

Necrosis cutánea por warfarina

Acta Médica Colombiana, 2014
La necrosis cutánea por warfarina aparece entre 0.01-0.1% de los pacientes, afecta más a mujeres con obesidad y antecedentes de enfermedad tromboembólica luego del quinto día de su inicio. Se debe a un imbalance transitorio de los sistemas anticoagulante y procoagulante, caracterizado por flictenas hemorrágicas en zonas con tejido graso.
Edison Muñoz, Oscar Jairo Valencia, Luis Toro, Luis Alfonso Correa, Juan Carlos Wolff   +4 more
openaire   +3 more sources

Graves’ Disease and Treatment Effects on Warfarin Anticoagulation

Case Reports in Medicine, Volume 2014, Issue 1, 2014., 2014
Background. Hyperthyroidism causes an increased hypoprothrombinemic response to warfarin anticoagulation. Previous studies have demonstrated that patients with hyperthyroidism require lower dosages of warfarin to achieve a therapeutic effect. As hyperthyroidism is treated and euthyroidism is approached, patients may require increasing warfarin dosages ...
Amanda Howard-Thompson, Alexis Luckey, Christa George, Beth A. Choby, Timothy H. Self, Arduino A. Mangoni   +5 more
wiley   +1 more source

Sobreanticoagulación con Warfarina

Archivos de Medicina (Manizales), 2009
El uso de la warfarina está asociado con la aparición de Reacciones Adversas Medicamentosas como la sobreanticoagulación, esto genera más morbilidad, hospitalizaciones y mayor riesgo de sangrado en los ancianos a través de asociaciones con otras enfermedades e interacciones con medicamentos y alimentos.
openaire   +2 more sources

Hematoma epidural espinal en paciente con tratamiento anticoagulante con warfarina. A propósito de un caso

Acta Médica del Centro, 2022
Introducción: el hematoma epidural espontáneo es una enfermedad poco habitual que puede acompañarse de compresión medular. Numerosas causas pueden ocasionarla, una es el mal control de los anticoagulantes orales.
Maryla Martínez-Fortún Amador, Marcos Luis García, Suyen Jiménez Cruz, Yuniesky Hernández González   +3 more
doaj  

The Prevalent New‐User Design to Study Drug–Drug Interactions: The Example of Sulfonylureas and Warfarin Interaction on the Risk of Severe Hypoglycemia

Pharmacoepidemiology and Drug Safety, Volume 33, Issue 10, October 2024.
ABSTRACT Purpose The optimal design for pharmacoepidemiologic drug–drug interactions (DDIs) studies is unclear. Using the association between concomitant use of sulfonylureas and warfarin and the risk of severe hypoglycemia as a case study, a DDI with little or no clinical impact, we tested whether the prevalent new‐user design can be applied in the ...
Wanqi Wang, Ying Cui, Oriana Hoi Yun Yu, Samy Suissa, Antonios Douros   +4 more
wiley   +1 more source

Use of drugs with pharmacogenomics (PGx)‐based dosing guidelines in a Danish cohort of persons with chronic kidney disease, both on dialysis and not on dialysis: Perspectives for prescribing optimization

Basic &Clinical Pharmacology &Toxicology, Volume 134, Issue 4, Page 531-542, April 2024.
Abstract Aim The objective of this registry study is to assess the utilization of pharmacogenomic (PGx) drugs among patients with chronic kidney disease (CKD). Methods This study was a retrospective study of patients affiliated with the Department of Nephrology, Aalborg University Hospital, Denmark in 2021. Patients diagnosed with CKD were divided into
Niels Westergaard, Morten Baltzer Houlind, Lona Louring Christrup, Helle Gybel Juul‐Larsen, Charlotte Strandhave, Anne Estrup Olesen   +5 more
wiley   +1 more source

Factors influencing vitamin K antagonists therapy / Factori care influențează terapia cu antagoniști ai vitaminei K

Romanian Journal of Laboratory Medicine, 2015
Antagoniștii vitaminei K (AVK) sunt utilizați pe scară largă pentru profilaxia primară și secundară a trombembolismului, efectul lor anticoagulant fiind monitorizat prin intermediul INR.
Brudașcă Ioana
doaj   +1 more source

Necrosis cutánea y peneana inducidas por warfarina

Acta Médica Colombiana, 2014
Presentamos el caso de un hombre adulto mayor con múltiples episodios de trombosis venosa y arterial en diferentes localizaciones, quien desarrolló necrosis cutánea extensa y peneana pocos días después del uso de un antagonista de vitamina K (warfarina). Como parte del estudio de trombofilia se observó deficiencia de proteína C y S.
Alfredo Pinzón, Catalina Arias, Ana María Cárdenas   +2 more
openaire   +3 more sources

Factores genéticos y ambientales asociados con respuesta a warfarina en pacientes colombianos

Iatreia, 2010
Introducción: la warfarina es un anticoagulante de difícil manejo por su estrecho margen terapéutico y los numerosos factores que influyen en la respuesta.
Carlos Isaza, Leonardo Beltrán, Gloria Porras, Alfredo Pinzón, Alvaro Vallejos, Jorge Machado, Julieta Henao   +6 more
doaj