Results 51 to 60 of about 404,362 (163)
Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice
Advanced Science, EarlyView.CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu +8 more
wiley +1 more source
BMEMat, EarlyView.NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu +13 more
wiley +1 more source
Study of Damage to Shutters Exposed to a Vegetation Fire: Definition of Vulnerability Thresholds
Fire and Materials, EarlyView.ABSTRACT This study examines the fire behavior of wooden, PVC, and aluminum shutters through laboratory and large‐scale experiments. Laboratory tests were conducted using a cone calorimeter to assess the ignitability of the PVC and wooden shutters, focusing on the critical heat flux of ignition, ignition time and critical Flux Time Product (FTP ...
C. Luciani +5 more
wiley +1 more source
, 2014 Objectives: To trace the development of the practice and theoretical basis of dry needling by means of an examination of the literature. Findings: The term dry needling arose from the need to provide a contrast to the injection of a fluid through a ...
Legge, David (R18074)
core +1 more source
Warm-up and performance in competitive swimming [PDF]
, 2014 Warm-up before physical activity is commonly accepted to be fundamental, and any priming practices are usually thought to optimize performance. However, specifically in swimming, studies on the effects of warm-up are scarce, which may be due to the ...
Izquierdo, Mikel +4 more
core +1 more source
Flavour and Fragrance Journal, EarlyView.Acupuncture at Feishu (BL13), Shenshu (BL23), Yingxiang (LI20), and Dazhui (GV14) alleviates allergic rhinitis by activating the AMPK/PGC‐1α/NRF1/TFAM signalling axis. This activation improves mitochondrial biogenesis and function, reduces mtROS‐mediated oxidative stress, restores ATP production and respiratory complex I/IV activity, suppresses IgE and
Fengying Zhang +3 more
wiley +1 more source
, 2017 Chunhui He,1,* Hua Ma2,* 1Internal Medicine of Traditional Chinese Medicine, 2Medical Image Center, The First Affiliated Hospital of Xinjiang Medical University, Wulumuqi, People’s Republic of China *These authors contributed equally to this work ...
He C, Ma H
core
International Journal of Climatology, EarlyView.Compound dry‐hot events (CDHEs) exerted severer damage on vegetation productivity for temperate shrublands, savannas and grasslands in drylands. Land‐atmosphere coupling was associated with severer negative impacts of CDHEs through soil moisture–temperature feedback, especially for dry‐event‐leading CDHEs.
Xue Xiao +3 more
wiley +1 more source
Combined use of skin needling and an autologous platelet gel in acne scarring treatment
, 2010 Introduction. Acne can produce permanent scars that are surprisingly difficult to treat. At present, there are many options available for acne scarring treatment. A relatively new treatment, called skin needling, seems to be appropriate for the treatment
PASTORE, FRANCESCO +10 more
core
Procedural Treatments: Bleb Needling
, 2009 Filtering blebs fail due to wound healing responses along the path of aqueous outflow (Fig. 37.1). there can be significant subconjunctival fibroblast proliferation and biosynthesis of collagen and other extracellular matrix materials in the area of ...
Giaconi, JoAnn A +3 more
core +1 more source