The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
The impact of warm-up with the volleyveilig approach on upper extremity function in female volleyball players. [PDF]
Baharmast A, Sedaghati P, Ahmadabadi S.
europepmc +1 more source
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang +16 more
wiley +1 more source
Weekly Heart Rate Variability and Training Zone Analysis in U-15 Soccer Players: The Predictive Value of Combined Warm-up Protocols for Optimizing Cardiovascular Monitoring. [PDF]
Zarei H +3 more
europepmc +1 more source
Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao +8 more
wiley +1 more source
Mental imagery and breathing exercises integrated into a standardized warm-up routine enhance sympathetic activation and optimize muscular performance in firefighters. [PDF]
Biéchy JP +6 more
europepmc +1 more source
Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen +8 more
wiley +1 more source
Association of Participation in Warm-Up Exercises with Complications, Subsequent Injury Frequency, and Recovery Duration Among Athletes with a History of Injury: A Physical Activity Epidemiology Study Using Secondary Survey Data. [PDF]
Park EH, Kwon D, Kwon J.
europepmc +1 more source
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong +10 more
wiley +1 more source
Self selected music during warm up improves anaerobic performance in female handball players across time of day. [PDF]
Bougrine H +7 more
europepmc +1 more source

