Results 201 to 210 of about 64,384 (262)

Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7

Advanced Science, EarlyView.
Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim, Gaeun Lee, Saemin An, Hanseul Park, Hongwon Kim, Jisung Kim, Soi Kang, Sumin Kim, Daeyeol Kwon, Jeonghyun Park, Yerim Hwang, Seonghun Kim, Xiuwen Yuan, Jaehoon Jeong, Hamin Lee, Hui Kwon Kim, Jongpil Kim   +16 more
wiley   +1 more source

Thermodynamic-microphysical coupling mechanisms of hydrometeor phase transitions during persistent wind turbine icing. [PDF]

Sci Rep
Tang J, Feng T, Wang L, Li L, Zhang H, Jian Z, Ouyang Y.   +6 more
europepmc   +1 more source

A Sustainable Bio‐Based Epoxy Thermoset as a High‐Performance Alternative to BPA‐Based Resins

Advanced Science, EarlyView.
A rigid–flexible bio‐based epoxy network integrates soybean oil, lignin, and maleic anhydride to overcome the strength–toughness–sustainability trade‐off of conventional BPA epoxy. The thermoset delivers excellent performance as both a structural adhesive and a matrix for glass‐fabric composites, while enabling pH‐responsive degradation, environmental ...
Jiyun Qi, Xinyi Hui, Xipeng Zhang, Jia‐Long Wen, Tong‐Qi Yuan   +4 more
wiley   +1 more source

Contrasting patterns in kelp consumption across latitude by two barren forming sea urchin species. [PDF]

Sci Rep
Butler C, Wang Y, Brown CJ, Vergés A, Ling S, Hurd CL, Bennett S.   +6 more
europepmc   +1 more source

Regulating Droplet Dynamics via Wormlike Micelle Networks: From Splash Suppression to Precise Confined Spreading

Advanced Science, EarlyView.
As displayed in Graphical Abstract image.tif, a molecular‐design strategy precisely tailors high‐speed droplet dynamics through programmed surfactant co‐assembly. The structural transition into an entangled wormlike micelle network completely suppresses stochastic splashing on fibrous substrates.
Shuling Liu, Beibei Xie, Xingyue Lou, Yu Deng, Lei Wang, Jiawei Li, Dongming Qi   +6 more
wiley   +1 more source

Admixture and Selection Driven by El Niño-Southern Oscillation Events Shape the Genetic Structure of <i>Octopus mimus</i>-<i>O. hubbsorum</i> Complex Across the Humboldt and South Equatorial Current Transition Zone. [PDF]

Ecol Evol
Ruiz-Mendoza J, Bieker VC, Morin-Lagos JG, Cardoso F, Vélez-Zuazo X, Alfaro-Shigueto J, Arellano-Martínez M, Siccha-Ramirez R, Martin MD, Ramirez JL.   +9 more
europepmc   +1 more source

Historical data reveal extirpation of foundation species and kelp forest community deborealization in a coastal hotspot. [PDF]

Ecol Appl
Timmer B, Reshitnyk LY, Neufeld CJ, Baum JK.   +3 more
europepmc   +1 more source

Ageing Analysis of Light-Emitting Diodes Used in Consumer Lighting. [PDF]

Materials (Basel)
Ludvig LÁ, Forczek B, Harsányi G.
europepmc   +1 more source

Efficacy of acupuncture-based traditional Chinese medicine therapies for chronic fatigue syndrome: a systematic review and meta-analysis. [PDF]

Front Neurol
Li Y, Liang G, Xiao T, Xu L.
europepmc   +1 more source

A Complex Case of Anti-e Mimicking Autoantibody Development Leading to Warm Autoimmune Hemolytic Anemia: Case Report. [PDF]

Acta Haematol
Hale I, Kunes KL, Sabile J, Dougherty J, Wong T, Heinrich M.   +5 more
europepmc   +1 more source