Results 81 to 90 of about 245,760 (237)

Therapeutic effects of different acupuncture methods on chronic nonspecific low back pain: A network meta-analysis

Journal of Orthopaedic Surgery and Research
Background Low back pain has become a globally challenging health problem, and about 90% of cases are nonspecific. Due to the risks associated with opioid use and the limited effectiveness of drug treatment, acupuncture and other non-drug methods have ...
Kaixuan Zhang, Xingxing Lin, Ziwei Liu, Yu Fu, Leichao Wang, Danning Zhang, Qiang Zhang, Feng Zhang, Xinle Wang, Baoqiang Dong   +9 more
doaj   +1 more source

The efficacy of acupuncture therapies in cervical spondylotic radiculopathy: A network meta-analysis

Heliyon
Objective: To evaluate the efficacy of acupuncture-related therapy in the Bayesian setting by means of a network Meta-analysis. Methods: Relevant clinical randomized controlled trials(RCTs) of acupuncture-related therapy for Cervical Spondylotic ...
Yingtong Lin, Sha Zhong, Chaoyuan Huang, Gangyu Zhang, Ganghui Jiang   +4 more
doaj   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source

Heat Stress Promotes Fibroblast‐Derived WNT5A Secretion Through m6A Modification to Activate Melanogenesis

Advanced Science, EarlyView.
Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan, Yaqing Wen, Yushan Zhang, Lan Zhang, Jianjian Zhu, Zhen Tang, Ling Jiang, Chuhan Fu, Shu Zhou, Keyi Zhang, Jiangfeng Huang, Li Lei, Jing Chen, Qinghai Zeng   +13 more
wiley   +1 more source

Study on regulatory effects of warm needling moxibustion on chondrocyte senescence in rats with knee osteoarthritis

针刺研究
ObjectiveTo investigate the effect of warm needling moxibustion on chondrocyte senescence in rats with knee osteoarthritis （KOA）， and to compare its efficacy with that of mild moxibustion.MethodsForty-eight Wistar rats were randomly assigned to ４ groups （
Feng Tian-shi, Li Jun-lei, Jia Ye-juan, Tao Yuan, Xu Jing   +4 more
doaj   +2 more sources

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

Advanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan, Chaowen Bai, Yifei Zhu, Chenyang Xu, Sonngtao Li, Qize Sun, Chang She, Jinyu Bai, Cong Cao, Yitian Yang, Xiaozhong Zhou   +10 more
wiley   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Efficacy and safety of warm needle acupuncture for allergic rhinitis: A systematic review and meta-analysis with trial sequential analysis

Heliyon
Backgrounds: Warm needle acupuncture is a distinct form of acupuncture therapy in which, after the needle is inserted into the acupoint, a lit moxa stick is placed on the needle's handle. Objective: This research aims to provide evidence for efficacy and
Shasha Yang, Qinwei Fu, Jing Wu, Qinxiu Zhang, Hua Deng, Shucheng Chen, Huihui Yang, Mingling Yan, Linjie Zhang   +8 more
doaj   +1 more source

Neurophysiological Effects of Dry Needling: A Systematic Review and Metanalysis

Gabriel Rabanal-Rodríguez is recipient of a researcher training scholarship from Universidad Complutense de Madrid and Banco Santander (CT25/24).Objective : To evaluate the neurophysiological effects associated with dry needling.
Kocot-Kępska, Magdalena, Gómez Chiguano, Guido Fabián, Plaza Manzano, Gustavo, Rabanal Rodríguez, Gabriel, Navarro Santana, Marcos José, Fernández de las Peñas, César, Valera Calero, Juan Antonio   +6 more
core   +1 more source

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

Advanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li, Nana Zhang, Zexin Bian, Baobao Geng, Liyun Cao, Peipei Liu, Zengming Li, Yan Zhao, Jun Tan   +8 more
wiley   +1 more source