Results 101 to 110 of about 245,760 (237)
Advanced Science, EarlyView.SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang +9 more
wiley +1 more source
Effectiveness of warm needling acupuncture for pain relief in patients with diabetic peripheral neuropathy: A protocol of systematic review. [PDF]
Medicine (Baltimore), 2020 Wang LQ, Wang F, Wang XH.
europepmc +1 more source
Advanced Science, EarlyView.IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia +8 more
wiley +1 more source
Introduction Lateral epicondylalgia (LE) is commonly presented with myofascial trigger points (MTrPs) among adults. Dry needling (DN) is used less frequently as a first-line treatment in LE with trigger points, and the short and long-term effectiveness ...
Ramprasad Muthukrishnan +4 more
core +1 more source
Advanced Science, EarlyView.This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu +23 more
wiley +1 more source
THE INVESTMENT POTENTIAL OF WARM-SEASON GRASSES FOR HILL-LAND BEEF PRODUCERS [PDF]
The investment potential of warm-season grasses is compared with that of cool-season grasses, with special emphasis on hill-land beef production. In addition to evaluating relative costs and returns for various grazing systems, a sensitivity analysis is ...
Romero, Rafael F. +2 more
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Advanced Science, EarlyView.The graphical abstract illustrates that sublethal thermal stress after iRFA upregulates the chaperone CRYAB in residual HCC cells, which stabilizes β‐catenin and drives a dual pathological program, including EMT and N2‐TAN polarization, thereby leading to heterotypic CTC cluster formation. The MMP‐9‐responsive hydrogel (XB@Gel) delivers XAV‐939 and BMS‐
Hui Chen +8 more
wiley +1 more source
Certificate appointing Cyrus Walker as Postmaster of Warm Springs, Oregon [PDF]
, 1886 Cyrus Walker was the oldest son of the early Oregon Territory missionaries Elkanah and Mary Richardson Walker. He grew up at Tshimakain in the 1830s-40s, where he learned the native Spokane language. After joining the U.S.
Warm Springs Post Office Department
core +1 more source
Advanced Science, EarlyView.Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
Equity versus Warm Glow in Intergenerational Giving [PDF]
In different treatments of an intergenerational common resource experiment, monetary payoff maximization by each generation causes either negative or positive externalities for future generations.Two behavioral types have been observed previously in ...
Sadrieh, A.
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