Results 151 to 160 of about 481,746 (305)

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Oregon Task Force on Global Warming: report to the Governor and Legislature

open access: yes, 1990
pt 1. Possible impacts on Oregon from global warming -- pt. 2. State agency recommendations and proposed actionsThis archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program.

core  

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Global warming is global energy storage

open access: yes, 2008
The global air temperature increase is an inadequate measure of global warming, which rather should be considered in terms of energy. The ongoing global warming means that heat has been accumulating since 1880, in air, ground, and water.
Gervet, Bruno, Nordell, Bo
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Chapter 5: Global warming: The neglected supply side [PDF]

open access: yes
This chapter addresses one of the most long-term issues for mankind: global warming. The chapter points out that most existing analyses have neglected the supply side.
Hans-Werner Sinn   +6 more
core  

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