Results 61 to 70 of about 993,218 (302)

Are philosophers responsible for global warming? [PDF]

open access: yes, 2008
Global warming has come about as a result of rapid population increase plus our whole modern way of life, all made possible by modern science. In order to tackle global warming successfully, we need a new kind of inquiry that gives intellectual priority ...
Maxwell, N.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Assessing the impact of climate and population changes on heatstroke incidence in Saitama City, Japan

open access: yesEnvironmental Research: Climate
There is growing concern about heat waves caused by climate change. In Japan, the population is rapidly aging, and protecting older people from heatstroke is attracting public attention.
Keita Honjo   +2 more
doaj   +1 more source

The Combined Effects of Increased pCO2 and Warming on a Coastal Phytoplankton Assemblage: From Species Composition to Sinking Rate

open access: yesFrontiers in Marine Science, 2021
In addition to ocean acidification, a significant recent warming trend in Chinese coastal waters has received much attention. However, studies of the combined effects of warming and acidification on natural coastal phytoplankton assemblages here are ...
Yuanyuan Feng   +10 more
doaj   +1 more source

The global warming hiatus: Slowdown or redistribution? [PDF]

open access: yes, 2016
Global mean surface temperatures (GMST) exhibited a smaller rate of warming during 1998-2013, compared to the warming in the latter half of the 20th Century.
Boyer, Tim   +8 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Soil Warming Accelerates Biogeochemical Silica Cycling in a Temperate Forest

open access: yesFrontiers in Plant Science, 2019
Biological cycling of silica plays an important role in terrestrial primary production. Soil warming stemming from climate change can alter the cycling of elements, such as carbon and nitrogen, in forested ecosystems. However, the effects of soil warming
Jonathan Gewirtzman   +11 more
doaj   +1 more source

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