Results 51 to 60 of about 355,012 (317)

High-speed target detection algorithm based on the RFT for SABBEWR

open access: yesThe Journal of Engineering, 2019
In space-air-based bistatic early warning radar (SABBEWR) application, the standard Radon–Fourier transform (RFT) can effectively reduce the deterioration of target-detection performance caused by the serious range migration.
Wantian Wang   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Gedanken zu dem Nomen ... "Samen, Nachkommen" in Genesis

open access: yesOld Testament Essays, 2017
In Genesis the noun זרע appears fifty-nine times, both in MT, Sam and (the Hebrew source text of ) LXX.  The ninety-five occurrences consist of „priestly“ and „non-priestly“ texts.
Wilfried Warning
doaj  

Comparison of Experienced and Novice Drivers’ Visual and Driving Behaviors during Warned or Unwarned Near–Forward Collisions

open access: yesSensors, 2023
Forward collision warning systems (FCWSs) monitor the road ahead and warn drivers when the time to collision reaches a certain threshold. Using a driving simulator, this study compared the effects of FCWSs between novice drivers (unlicensed drivers) and ...
Jordan Navarro   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

A Concept of an Interactive Threat Warning System [PDF]

open access: yesBezpieczeństwo i Technika Pożarnicza, 2018
Aim: The aim of this article is to present the results of the initial research aiming at gathering civilian population’s opinions on whether it is necessary and possible to introduce into common use smart-phone and desktop applications for real-time ...
Henryk Wyrębek, Paweł Szmitkowski
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Meteorological clutter suppression method for ball-borne radar based on Kalmus filter

open access: yesThe Journal of Engineering, 2019
Aimed at the problem that the unmanned aerial vehicle (UAV) target is difficult to be detected in the meteorological clutter because of their close velocity, a new detection method is proposed for the ball-borne radar based on Kalmus filter. Firstly, the
Xiaohan Zhang   +4 more
doaj   +1 more source

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