Results 71 to 80 of about 355,012 (317)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Optimizing timing for emergency vehicle approaching warnings
Acta Polytechnica CTU ProceedingsEmergency driving is a demanding task. The ITS service Emergency Vehicle Approaching provides drivers with an in-car warning that an emergency vehicle is approaching.
Kajsa Weibull +2 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
EchoGéoFloods that hit the Valencia region (Spain) on 29 October 2024 took a heavy toll in terms of human lives (229 deaths) and material damage (€22 billion euros).
Johnny Douvinet +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
A new approach to designing lateral collision warning systems
, 2007 According to the National Highway Traffic Safety Administration (NHTSA), more than 43% of all fatal accidents reported in 2001 involved a lane or road departure.
Stanton, Neville A +11 more
core +1 more source
Systems and Sensors for Debris-flow Monitoring and Warning
Sensors, 2008 Debris flows are a type of mass movement that occurs in mountain torrents. They consist of a high concentration of solid material in water that flows as a wave with a steep front.
Lorenzo Marchi, Massimo Arattano
doaj
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Gender equity in disaster early warning systems
, 2015 Capacities of societies, communities and individuals or a social-ecological system to deal with adverse consequences and the impacts of hazard events define the resilience.
De Silva, Kushani +2 more
core
PREDICTING HYDROLOGICAL HAZARDS TO PREVENT EMERGENCY SITUATIONS AND THEIR ENVIRONMENTAL CONSEQUENCES
Надежность и качество сложных системBackground . The urgency of this study is conditioned by the unresolved large-scale problems of exploration, engineering, and adoption of the effective monitoring and forecasting systems, as well as timely warning of hazardous hydrological events, such ...
Aleksandr V. Tyurin +3 more
doaj +1 more source