Results 41 to 50 of about 415,667 (251)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Laws and regulations governing rotation of health warning labels on cigarette packs in the Region of the Americas

Revista Panamericana de Salud Pública, 2022
Objectives. To provide detailed information about how countries in the Region of the Americas are fulfilling the requirements set out in the guidelines for the implementation of Article 11 of the WHO Framework Convention on Tobacco Control in relation to
Fernanda Alonso, Kevin Welding, Joanna E. Cohen   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Americans’ Perspectives on Online Media Warning Labels

Behavioral Sciences, 2022
Americans are pervasively exposed to social media, news, and online content. Some of this content is designed to be deliberately deceptive and manipulative.
Jeremy Straub, Matthew Spradling
doaj   +1 more source

Textual health warning labels on snus (Swedish moist snuff): do they affect risk perception? [PDF]

, 2018
Background: To strengthen the risk message on snus warning labels, the European Union in 2016 removed “can” from the warning “This tobacco product (can) damages your health and is addictive.” We tested how these and other textual warnings affect risk ...
Nilsen, Connie Villemo, Nilsen, Connie V, Teigen, Karl H, Connie Villemo Nilsen, Oddgeir Friborg, Svartdal, Frode, Karl Halvor Teigen, Friborg, Oddgeir, Teigen, Karl Halvor, Frode Svartdal   +9 more
core   +1 more source

Warning labels

, 2023
To allow consumers to make informed decisions and to encourage them to make healthier choices many product packages contain (warning) labels. These can vary from nutrition labels and ingredient lists on food and drinks packaging to health warnings on ...
Mollen, S.; id_orcid
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Impact of warning labels on sugary beverages on risk perception, attention, and purchase intentions [PDF]

Innovative Marketing
The issue of warning labels on sweet beverage product packaging needs to be tested to determine its role in reducing product consumption. This study aims to examine the impact of warning labels on attention, risk perception, and purchase intention for ...
Herry Novrianda, Faisal Muttaqin, Aan Shar   +2 more
doaj   +1 more source