Results 101 to 110 of about 1,836,445 (279)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The effect of sugar beet seed treatments on their vigour

open access: yesPlant, Soil and Environment, 2003
Sugar beet seeds of three varieties (Jastra, Jamira, PNMono1) were rubbed, primed, washed and primed after rubbing. All used methods of seed treatment changed pericarp characteristics such as water potential, density, moisture and content of chemicals ...
A. Orzeszko-Rywka, S. Podlaski
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Quality assessments of untreated and washed quinoa (Chenopodium quinoa) seeds based on histlogical and foaming capacity investigations [PDF]

open access: yes
Quinoa seed has a high nutritional value, but has a coating of bitter-tasting saponins, making it unpalatable. Therefore the seeds are usually processed in order to remove the naturally occurring saponins from the seeds.
Groot, M.J.   +5 more
core   +1 more source

Communal residential laundry washing and drying : can it provide demand-side electrical load flexibility? [PDF]

open access: yes, 2011
Changes in lifestyle have led to increased use and ownership rates of domestic appliances resulting in increasing electrical consumption in the residential sector. An important element of this consumption is due to domestic washing and drying of laundry.
Borg, Simon Paul   +5 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Are you Buying a Washing Machine? [PDF]

open access: yes, 1936
PDF pages ...
Beall, Thelma, Beard, Ruth
core  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Influence of hydrocyclone underflow jet diameter on washing efficiency of steam coal from the Cige¾ Colliery [PDF]

open access: yesActa Montanistica Slovaca, 2000
The contribution describes results of steam coal washing in water-only (WO) cyclone at various diameter of underflow jets. The overflow jet with the diameter of 68 mm was used.
Jakabský Štefan   +2 more
doaj  

The Options for UK Domestic Water Reduction: A Review [PDF]

open access: yes, 2005
Demand pressure on UK water supplies is expected to increase in the next 20 years driven by increasing population, new housing development and reducing household size. Regionally and locally migration will also afect demand particularly in the South-East.
McDonald, A.   +3 more
core  

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