Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The effect of sugar beet seed treatments on their vigour
Plant, Soil and Environment, 2003 Sugar beet seeds of three varieties (Jastra, Jamira, PNMono1) were rubbed, primed, washed and primed after rubbing. All used methods of seed treatment changed pericarp characteristics such as water potential, density, moisture and content of chemicals ...
A. Orzeszko-Rywka, S. Podlaski
doaj +1 more source
Designing a greener product: the Hoover 'New Wave' washing machine range [PDF]
, 1996 Hoover is one of the best known manufacturers of domestic appliances in Britain and has made washing machines at its Merthyr Tydfil factory since 1948.
Roy, Robin
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Optimisation of solvolysis for recycling carbon fibre reinforced composites [PDF]
, 2016 Solvolysis processes have been used to degrade the resin of two different varieties of epoxy based carbon fibre reinforced composite (CFRC) materials. A degradation of up to 98% has been achieved when processing material at a temperature of 320 °C using ...
Keith, Matthew J. +2 more
core
Auditing the Compliance of Nursing Staff on Hand Washing Technique during (COVID- 19) Pandemic [PDF]
, 2020 Hanaa Mohamed Ahmed
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Influence of hydrocyclone underflow jet diameter on washing efficiency of steam coal from the Cige¾ Colliery [PDF]
Acta Montanistica Slovaca, 2000 The contribution describes results of steam coal washing in water-only (WO) cyclone at various diameter of underflow jets. The overflow jet with the diameter of 68 mm was used.
Jakabský tefan +2 more
doaj
Quality assessments of untreated and washed quinoa (Chenopodium quinoa) seeds based on histlogical and foaming capacity investigations [PDF]
Quinoa seed has a high nutritional value, but has a coating of bitter-tasting saponins, making it unpalatable. Therefore the seeds are usually processed in order to remove the naturally occurring saponins from the seeds.
Groot, M.J. +5 more
core +1 more source