Results 31 to 40 of about 33,850 (239)

Rectal cancer treatment: new insights on watch-and-wait and organ-preserving treatment strategies [PDF]

, 2023
In the Netherlands, each year about 3000 patients are diagnosed with rectal cancer, a tumour in the last part of the colon. Often, the treatment involves neoadjuvant treatment, radiotherapy sometimes in combination with chemotherapy, followed by surgery ...
Custers, Petronella Antonia
core   +5 more sources

Potential and limitations of deep learning-based MRI in assessing complete response and the “watch and wait” strategy for rectal cancer

结直肠肛门外科
With the widespread adoption of neoadjuvant therapy and the development of combined treatment strategies such as total neoadjuvant therapy, targeted therapy, and immunotherapy, the rate of tumor complete response in patients with locally advanced rectal ...
Zhao Xinzhe, Diao Dechang
doaj   +1 more source

Short-term outcomes from the 'Watch and Wait' (WoW) study: prospective cohort study. [PDF]

BJS Open
BACKGROUND: Despite absence of level 1 evidence on the long-term oncological safety of non-operative management for rectal cancer (watch and wait), increased implementation has occurred globally over the past decades.
Rydbeck D, Azhar N, Blomqvist L, Chabok A, Folkesson J, Gerdin A, Hermus L, Matthiessen P, Martling A, Nilsson PJ, Angenete E.   +10 more
europepmc   +2 more sources

Exploring the Psychosocial Needs of Adults with Haematology Cancer under Watch and Wait

, 2021
To explore and identify unmet needs in adults with haematology cancer under the watch and wait pathway through semi-structured ...
Dr Sanchia Biswas, Dr Anna Tickle, Katie Russell, Nima Golijani-Moghaddam   +3 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Personalized medicine for locally advanced rectal cancer: five years of complete clinical response after neoadjuvant radiochemotherapy—a case report with a literature review

Frontiers in Surgery
We present a case report of a 73-year-old male patient with a complete clinical response following neoadjuvant radiochemotherapy of mid-rectal adenocarcinoma.
Dennis Obonyo, Verena Uslar, Dirk Weyhe, Navid Tabriz   +3 more
doaj   +1 more source

Adjuvant therapy versus watch-and-wait post surgery for stage III melanoma: a multicountry retrospective chart review

Melanoma Management, 2019
Aim: To describe treatment patterns among patients with stage III melanoma who underwent surgical excision in years 2011–2016, and assess outcomes among patients who subsequently received systemic adjuvant therapy versus watch-and-wait.
Peter Mohr, Felix Kiecker, Virtudes Soriano, Olivier Dereure, Karmele Mujika, Philippe Saiag, Jochen Utikal, Rama Koneru, Caroline Robert, Florencia Cuadros, Matias Chacón, Rodrigo U Villarroel, Yana G Najjar, Lisa Kottschade, Eva M Couselo, Roy Koruth, Annie Guérin, Rebecca Burne, Raluca Ionescu-Ittu, Maurice Perrinjaquet, Jonathan S Zager   +20 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

«Watch and Wait» strategy in the management of rectal adenocarcinoma [PDF]

, 2021
Currently, the standard management of locally advanced adenocarcinoma of the middle and lower rectum consists in first intention of pre-operative radio-chemotherapy. This treatment is then usually followed by rectal surgery with removal of the mesorectum.
LABILLE, Virginie, LOLY, Catherine, Louis, Edouard   +2 more
core   +1 more source