Results 41 to 50 of about 18,083 (294)
Watchful surgery in asymptomatic mitral valve prolapse
Frontiers in Cardiovascular Medicine, 2023 The most common organic etiology of mitral regurgitation is degenerative and consists of mitral valve prolapse (MVP). Volume overload because of mitral regurgitation is the most common complication of MVP.
Myriam Carpenito +10 more
doaj +1 more source
Journal of Coloproctology, 2022 Abstract Background The surgery with total mesorectal excision recommended by R. J. Heald in 1982 is the gold standard. Rectal cancer (RC) surgery has a morbidity rate ranging from 6 to 35%, and it can cause functional issues such as sexual, urinary, and bowel dysfunction in the long term.
Manoel Álvaro de Freitas Lins Neto +3 more
openaire +3 more sources
American Journal of Hematology, EarlyView.ABSTRACT Limited data exist on how patients and physicians perceive immune thrombocytopenia (ITP) symptoms and treatment‐related burden. I‐WISh (ITP World Impact Survey) 2.0 surveyed 1018 patients and 431 physicians in 15 countries to characterize the impact of ITP and its treatments on patients.
Nichola Cooper +17 more
wiley +1 more source
Costs of abduction treatment in developmental dysplasia of the hip. Analysis of 900 patients
Annals of Medicine, 2023 Background Developmental dysplasia of the hip (DDH) is a disorder of hip development that leads to dysplasia, subluxation, or total hip dislocation. Early detection of DDH is important, and early initiation of abduction treatment is key to successful ...
Vilma Lankinen +6 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective The treatment landscape for systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) has evolved with increasingly available immunosuppressive therapies (ISTs) and antifibrotic treatments. However, their real‐world use remains unclear.
Corrado Campochiaro +17 more
wiley +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
Successive Medical Treatment Versus Watchful Waiting In Chronic Otitis Media With Effusion
, 2010 Objective: Management of otitis media with effusion (OME) is still an unresolved problem. Although watchful waiting gained popularity, it may not be applicable in the developing countries where medical and surgical treatments are being used more promptly.
Sennaroglu, Levent +6 more
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Abstract Health care is shifting towards a digital‐guided system, integrating digital diagnostics, biomarkers and therapeutics in many care pathways. However, despite rapid technological advancement and preliminary adoption accelerated by the COVID‐19 pandemic, a significant implementation gap persists. This narrative review explores the causes of this
Mees H. P. Stoop +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Clozapine is licenced for treatment‐resistant schizophrenia and psychosis in Parkinson's disease. In the United Kingdom, there is a mandatory requirement for absolute neutrophil count (ANC) and white blood cell count (WBC) monitoring to safeguard against agranulocytosis.
Stephen Murtough +29 more
wiley +1 more source
Interventions to Minimize Unnecessary Antibiotic Use for Acute Otitis Media: A Meta-Analysis
ChildrenBackgrounds/Objectives: Acute otitis media (AOM) is the leading reason antibiotics are prescribed to children. Despite guidelines advocating for watchful waiting and shorter antibiotic durations, overprescribing remains a concern. This meta-analysis aims
Theresa L. Morin +8 more
doaj +1 more source