Results 91 to 100 of about 21,684,099 (311)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Concepts d'efficience et de productivité de l'eau (synthèse bibliographique)
Biotechnologie, Agronomie, Société et Environnement, 2014 Water efficiency and productivity concepts. A review. Water efficiency and productivity indicators are used in many scientific disciplines, usually to account for water losses that occur during its use, or products generated per unit of water consumed ...
Kambou, D. +3 more
doaj
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Nonparametric approach for measuring the productivity change and assessing the water use efficiency in the irrigated areas of Tunisia [PDF]
In order to cope with the water scarcity, Tunisia has to manage efficiently the demand of the economic and social sectors mainly that of the agricultural irrigated activities. Within this context our investigation aims to analyze the technical efficiency,
Chemak, Fraj
core
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
, 1991 p. 49-53.The focus of this paper is to identify areas within agricultural irrigation, municipal and industrial use where recent innovations have demonstrated that research has the potential for making significant contributions to the future ...
Urban, L.V., Balliew, J.E.
core
Kansas Irrigation Water Use 1991. Irrigation Water Use in Kansas 1991
, 1992 "The data and charts shown in this publication were prepared from the Irrigation Water Use Reports submitted to the Division of Water Resources, Kansas Department of Agriculture for the 1991 calendar year."; Application ...
Kansas Water Office.
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Time of use tariffs: implications for water efficiency
, 2011 Water utilities undertake long term planning for water source security, often with forecast cycles of 20 to 30 years. Whilst this planning is generally involved with investigations of source water abstraction security and the need to build dams or to ...
Stewart, Rodney +2 more
core