Results 71 to 80 of about 21,684,099 (311)

Water use of wheat, corn and sunflower in the semiarid pampas [PDF]

open access: yesCiencia del Suelo, 2017
Crop water use in semiarid environments allows designing management strategies to improve water use efficiency. Our objective was to estimate wheat (Triticum aestivum L.), maize (Zea mays L.) and sunflower (Helianthus annuus L.) water use in the Semiarid
Alfredo A Bono   +2 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Productive Efficiency in Water Usage: An Analysis of Differences among Farm Types and Sizes in Georgia [PDF]

open access: yes
In Georgia, the price of irrigation water is equal to the cost of extraction, including pumping and diversion, storage, treatment, and delivery costs. These water-pricing conditions are repeated in locales around the world.
Moore, Rebecca, Price, Joseph
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Efficiency and equity considerations in pricing and allocating irrigation water [PDF]

open access: yes
Economic efficiency has to do with how much wealth a given resource base can generate. Equity has to do with how that wealth is to be distributed in society. Economic efficiency gets far more attention, in part because equity considerations involve value
Tsur, Yacov, Dinar, Ariel
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Biofuel, land and water: maize, switchgrass or Miscanthus?

open access: yesEnvironmental Research Letters, 2013
The productive cellulosic crops switchgrass and Miscanthus are considered as viable biofuel sources. To meet the 2022 national biofuel target mandate, actions must be taken, e.g., maize cultivation must be intensified and expanded, and other biofuel ...
Qianlai Zhuang, Zhangcai Qin, Min Chen
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Report (Texas Water Development Board)

open access: yes, 2004
A guide on the practices, techniques, programs, and technologies that will protect water resources, reduce the consumption of water, reduce the loss or waste of water, improve the efficiency in the use of water, and increase the recycling and reuse of ...
Texas Water Development Board
core  

Are Water Use Efficiency and Effectiveness Relatively Lower in Arid Zones? Comparative Analyses of the Water Productivity of Typical Crops

open access: yes
Agriculture is the largest water user of all sectors. In arid regions in particular, achieving efficient water use in agriculture is an important way to solve water scarcity.
Yanfei Zhang   +4 more
core   +1 more source

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