Results 91 to 100 of about 13,840,677 (308)

Improving water productivity: how do we get more crop from every drop [PDF]

open access: yes
Water management / Productivity / Irrigation management / Supplemental irrigation / Crop ...
International Water Management Institute (IWMI) / Comprehensive Assessment of Water Management in Agriculture
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Are We Seeking Pimatisiwin or Creating Pomewin? Implications for Water Policy

open access: yesInternational Indigenous Policy Journal, 2012
The purpose of this discussion is to describe the worldview and sacred relationship of the Cree people in Alberta, as well as how colonial policy has created despair (pomewin) in Aboriginal communities and a state of disconnectedness from the water.
Patti LaBoucane-Benson   +3 more
doaj  

IWRM challenges in developing countries: lessons from India and elsewhere [PDF]

open access: yes
Water resource management / Institutional development / Tube wells / Economic aspects / Policy ...
International Water Management Institute (IWMI).
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

(De)politicizing water: justice in times of water crisis

open access: yesFrontiers in Political Science
In times of climate change, water resources are shrinking at an alarming speed worldwide, making water a focal point of social and political contestation.
Henriette J. M. Schubert-Zunker   +1 more
doaj   +1 more source

IWMI Research Update: news of the progress and impact of IWMI's research [PDF]

open access: yes
Drought, Groundwater, Erosion, Wetlands, Irrigation management, Rainfed farming, Turkey, South East Asia, Sri Lanka ...
International Water Management Institute (IWMI).
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Water Figures Africa: news of IWMI’s work in Africa [PDF]

open access: yes
Water resource management, Water use, Governance, Food security, Irrigated farming ...
International Water Management Institute (IWMI).
core   +3 more sources

Review of the state of the art between sustainability and hydropower generation: A vision from Asia

open access: yesTecnología y ciencias del agua
Hydroelectric energy is a widely used technology in 180 countries benefiting in 2020, this source has 140 years of development, represents 16 % of the energy generated in the world and 63 % of renewables.
Sebastian Naranjo-Silva   +2 more
doaj   +1 more source

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