Results 31 to 40 of about 3,843,436 (244)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Pharmaceutics, 2016 Chitosan-based nanogels have been widely applied as drug delivery vehicles. Spray-drying of said nanogels allows for the preparation of dry powder nano-embedded microparticles.
Paromita Islam +3 more
doaj +1 more source
Water Policy, 2023 The paper aimed to evaluate the impacts of water pricing and quota policies under changing climatic conditions on the major production factors using economic-biophysical modeling.
Asiyeh Azizi +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Child and Adolescent Psychiatry and Mental Health, 2017 Background This qualitative study was nested within a randomized controlled trial (RCT) where two psychotherapeutic interventions (supportive counselling and prolonged exposure for adolescents) were provided by supervised nurses (who served as ‘nurse ...
Tanya van de Water +3 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Love Wave Ultraviolet Photodetector Fabricated on a TiO2/ST-Cut Quartz Structure
International Journal of Photoenergy, 2014 A TiO2 thin film deposited on a 90° rotated 42°45′ ST-cut quartz substrate was applied to fabricate a Love wave ultraviolet photodetector. TiO2 thin films were grown by radio frequency magnetron sputtering.
Walter Water, Yi-Shun Lin, Chi-Wei Wen
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Older patients with breast cancer: is there bias in the treatment they receive?
Therapeutic Advances in Medical Oncology, 2012 Breast cancer is the most frequent malignant tumor in women worldwide and as breast cancer incidence increases with increasing age, over 40% of new cases are diagnosed in women older than 65 years of age.
Christos Markopoulos MD, PhD +1 more
doaj +1 more source
Environmental fate of cefquinome: Adsorption and degradation
Frontiers in Environmental Science, 2022 Cefquinome (CEQ), the fourth generation of cephalosporins, has been widely used in practice for the treatment of bacterial infections due to its broad antimicrobial spectrum, stability, and stronger antibacterial activity.
Jicheng Qiu +13 more
doaj +1 more source