Results 51 to 60 of about 7,572,561 (328)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

NMR logging activation sets selection and fluid relaxation characteristics analysis of tight gas reservoirs: A case study from the Sichuan Basin

open access: yesNatural Gas Industry B, 2018
With complex lithology and reservoir types, as well as high concealment and heterogeneity, tight reservoirs in the Sichuan Basin involve significant uncertainties in gas–water relationship.
Yun Zhang, Jianmeng Wu, Guozhang Zhu
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Local microenvironment reactive zone engineering promotes water activation

open access: yesMaterials Reports: Energy
Beyond conventional electrocatalyst engineering, recent studies have demonstrated the effectiveness of manipulating the local reaction environment to enhance the performance of electrocatalytic reactions.
Jian Luo   +6 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Water in the 2003 Virginia General Assembly

open access: yes, 2003
The 2003 Virginia General Assembly convened on January 8 and adjourned on February 22, with a reconvened (“veto”) session on April 2. The legislature considered 3277 measures; 1585 passed and 1692 failed. The legislature also considered amendments to the
Virginia Water Resources Research Center
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Water in the 2007 Virginia General Assembly

open access: yes, 2007
The 2007 Virginia General Assembly convened January 10, adjourned February 24, and held a reconvened (“veto”) session on April 4. During the session, the Assembly considered 3427 measures (3069 introduced in this session and 358 continued from the 2006 ...
Virginia Water Resources Research Center
core  

Peracetic acid activation for degradation of emerging contaminants: Processes, performance and mechanism

open access: yes能源环境保护
The removal of emerging contaminants (ECs) from water has been a hotspot and a challenge in the field of environmental engineering. Advanced oxidation processes (AOPs) based on peracetic acid (PAA) activation can generate active species with strong ...
WU Jiabao, LIU Yanbiao*
doaj   +1 more source

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