Results 131 to 140 of about 5,219,909 (286)
Activities for Wetland Functions (title provided or enhanced by cataloger) [PDF]
These activities were designed to enhance the third chapter of a module about wetlands that covers flood and erosion control, fish and wildlife habitat, food webs, wetlands "supermarket", and recreation and aesthetics.
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Water quality evaluation in Mediterranean Lagoons using the Multimetric Phytoplankton Index (MPI): study cases from Sardinia [PDF]
, 2013 1 - Water quality in four Sardinian lagoons (western Mediterranean Sea) was assessed using the Multimetric Phytoplankton Index (MPI), which is consistent with the EU Water Framework Directive.
Bazzoni, Anna Maria +6 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Effect of the method of process on the control of microbial growth by water activity in foods [PDF]
, 1972 Two methods for preparation of intermediate moisture foods (IMF) were investigated; water absorption and water desorption technique. Results indicate that shelf stability of IMF systems might be enhanced by preparing foods by rehumidifying dehydrated ...
Labuzu, T. D.
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Environment InternationalPhthalate esters (PAEs) such as dimethyl phthalate (DMP), diethyl phthalate (DEP), bis-2(ethylhexyl) phthalate (DEHP), and di-n-octyl Phthalate (DOP) are synthetic chemicals used as solvent stabilisers and plasticizers in commercial and industrial ...
Cristian Ryan A. Argamino +6 more
doaj +1 more source
Water metabolism regulating mechanisms in hypokinesia [PDF]
The range of daily fluctuations of the proportion of the amount of consumed water and its content in the body was evaluated by means of a water metabolism regulation factor.
Krotov, V. P.
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Single-cell analysis in hypersaline brines predicts a water-activity limit of microbial anabolic activity. [PDF]
Sci Adv, 2023 Paris ER +11 more
europepmc +1 more source