Results 101 to 110 of about 1,677,787 (316)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Groundwater Availability at Brocton, Illinois (Edgar County) [PDF]

open access: yes, 2009
This project is an outgrowth of the Public Service Program of the Center for Groundwater Science (CGS) at the Illinois State Water Survey. For over 50 years, the CGS has provided groundwater information to any requesting individual, commercial facility ...
Midwest Technology Assistance Center
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Water for Texas Information Sheets

open access: yes, 2012
Information sheet describing how to request a groundwater availability model run. The request tasks the Texas Water Development Board to develop groundwater availability models for major and minor aquifers in ...
Texas Water Development Board
core  

Groundwater Availability at Mazon, Illinois (Grundy County) [PDF]

open access: yes, 2008
This project is an outgrowth of the Public Service Program of the Center for Groundwater Science (CGS) at the Illinois State Water Survey. For over 50 years, the CGS has provided groundwater information to any requesting individual, commercial facility ...
Midwest Technology Assistance Center
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Impacts of Reduced Water Availability on Lower Murray Irrigation, Australia [PDF]

open access: yes
This article evaluates irrigated agriculture sector response and resultant economic impacts of climate change for a part of the Murray Darling Basin in Australia.
Anna Lukasiewicz   +3 more
core  

Groundwater Availability at Fairmount, Illinois (Vermilion County) [PDF]

open access: yes, 2008
Open Restriction set for Item 109223 on 2019-01-07T17:18:42Z with date null by sharonh2@illinois.edu.This project is an outgrowth of the Public Service Program of the Center for Groundwater Science (CGS) at the Illinois State Water Survey.
Midwest Technology Assistance Center
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Groundwater Availability at Toledo, Illinois (Cumberland County) [PDF]

open access: yes, 2009
This project is an outgrowth of the Public Service Program of the Center for Groundwater Science (CGS) at the Illinois State Water Survey. For over 50 years, the CGS has provided groundwater information to any requesting individual, commercial facility ...
Midwest Technology Assistance Center
core  

Home - About - Disclaimer - Privacy