Results 121 to 130 of about 1,677,787 (316)

A Conceptual Framework to Assess Post‐Wildfire Water Quality: State of the Science and Knowledge Gaps

open access: yesWater Resources Research
Wildfire substantially alters aquatic ecosystems by inducing moderate to catastrophic physical and chemical changes. However, the relations of environmental and watershed variables that drive those effects are complex. We present a Driver‐Factor‐Stressor‐
Sarah M. Elliott   +4 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Groundwater Availability at La Rose (Marshall County) [PDF]

open access: yes, 2009
Submitted by Sharon Han (sharonh2@illinois.edu) on 2019-01-10T17:46:23Z No. of bitstreams: 1 LaRoseMTACReport.pdf: 3506772 bytes, checksum: ce194cad7759422955ef52428f6d6bff (MD5)This project is an outgrowth of the Public Service Program of the Center for
Midwest Technology Assistance Center
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Reducing poverty through integrated management of groundwater and surface water

open access: yes, 2014
The full poverty-fighting potential of existing irrigation schemes is not being realized?largely because of inequitable water distribution and unsustainable land and water management practices.
Global Water Partnership   +1 more
core  

Groundwater Availability at Montrose, Illinois (Effingham County) [PDF]

open access: yes, 2009
This project is an outgrowth of the Public Service Program of the Center for Groundwater Science (CGS) at the Illinois State Water Survey. For over 50 years, the CGS has provided groundwater information to any requesting individual, commercial facility ...
Midwest Technology Assistance Center
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Groundwater Availability at Hutsonville, Illinois (Crawford County) [PDF]

open access: yes, 2009
Submitted by Sharon Han (sharonh2@illinois.edu) on 2019-01-10T17:35:30Z No. of bitstreams: 1 HutsonvilleMTACReport.pdf: 945713 bytes, checksum: 4852e87faa9a2a3f746eaf584ae75319 (MD5)Made available in DSpace on 2019-01-10T17:35:30Z (GMT). No.
Midwest Technology Assistance Center
core  

Condições meteorológicas e tipo de solo na composição da uva 'Cabernet Sauvignon' Weather and soil effects on the composition of 'Cabernet Sauvignon' grape

open access: yesPesquisa Agropecuária Brasileira, 2013
O objetivo deste trabalho foi avaliar os efeitos das condições meteorológicas e do tipo de solo sobre características físico-químicas e compostos fenólicos da uva 'Cabernet Sauvignon' (Vitis vinifera). O experimento foi realizado em vinhedo implantado em
Rodrigo Vieira Luciano   +4 more
doaj  

Intra- and interspecific diversity in a tropical plant clade alter herbivory and ecosystem resilience

open access: yeseLife
Declines in biodiversity generated by anthropogenic stressors at both species and population levels can alter emergent processes instrumental to ecosystem function and resilience.
Ari Grele   +17 more
doaj   +1 more source

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