Results 91 to 100 of about 9,109,993 (303)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

A worldwide evaluation of basin-scale evapotranspiration estimates against the water balance method

, 2016
Summary Evapotranspiration (ET) plays a critical role in linking the water and energy cycles but is difficult to estimate at regional and basin scales. In this study, we present a worldwide evaluation of nine ET products (three diagnostic products, three
Wenbin Liu, Lei Wang, Jing Zhou, Yanzhong Li, F. Sun, G. Fu, Xiuping Li, Y. Sang   +7 more
semanticscholar   +1 more source

Monitoring water fluxes in rice plots under three different cultivation methods

Journal of Agricultural Engineering, 2013
Italy is the leading producer of rice in Europe with over half of total production, almost totally concentrated in a large traditional paddy rice area between the Lombardy and Piedmont regions, in the north-western part of the country.
Enrico Antonio Chiaradia, Daniele Ferrari, Gian Battista Bischetti, Arianna Facchi, Olfa Gharsallah, Marco Romani, Claudio Gandolfi   +6 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Variations of global and continental water balance components as impacted by climate forcing uncertainty and human water use

, 2016
. When assessing global water resources with hydrological models, it is essential to know about methodological uncertainties. The values of simulated water balance components may vary due to different spatial and temporal aggregations, reference periods,
H. Schmied, L. Adam, S. Eisner, G. Fink, M. Flörke, Hyungjun Kim, T. Oki, F. Portmann, R. Reinecke, C. Riedel, Qi Song, Jing Zhang, P. Döll   +12 more
semanticscholar   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Differences in the water-balance components of four lakes in the southern-central Tibetan Plateau

, 2016
. The contrasting patterns of lake-level fluctuations across the Tibetan Plateau (TP) are indicators of differences in the water balance over the TP. However, little is known about the key hydrological factors controlling this variability. The purpose of
S. Biskop, F. Maussion, P. Krause, M. Fink   +3 more
semanticscholar   +1 more source

Hydraulic conductance and the maintenance of water balance in flowers

bioRxiv, 2016
Flowers face desiccating conditions, yet little is known about their ability to transport water. We quantified variability in floral hydraulic conductance (Kflower) for 20 species from 10 families and related it to traits hypothesized to be associated ...
A. Roddy, C. Brodersen, T. Dawson
semanticscholar   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source