Results 71 to 80 of about 9,109,993 (303)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Estimation of water balance and water yield in the Reedy Fork-Buffalo Creek Watershed in North Carolina using SWAT

open access: yesInternational Soil and Water Conservation Research, 2018
To use water resources sustainably, it is important to understand the quantity of water resource spatially and temporally. Therefore, the work presented here attempts to preface future modeling applications within a watershed in North Carolina, by ...
Frederick Ayivi, M. Jha
semanticscholar   +1 more source

Water balance of the basin of Mandali/ east part of Iraq

open access: yesIraqi Journal of Physics, 2019
Mandali Basin is located between latitudes (33◦ 39' 00" and 33◦ 54' 55") to the north and longitudes (45ο 11' 00" and 45ο 40' 00") to the east; to the east of Diyala province at the Iraqi-Iranian border; the basin area is approximately 491 km2. From the
Qusai Y. AL-Kubaisi
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analisis Kebutuhan Pompa pada Sistem Penyaliran Tambang Terbuka dengan Persamaan Material Balance (Studi Kasus pada PT TIA)

open access: yesJurnal Fisika Flux, 2017
Tambang terbuka menghasilkan daerah bukaan tambang pada permukaan kerja (front). Kegiatan ini menimbulkan masalah genangan air yang bersumber dari air limpasan dan air tanah sehingga mengganggu aktivitas penambangan, kestabilan lereng dan keselamatan ...
Riswan Riswan, Dimas Aditya
doaj   +3 more sources

NUTRIENT BALANCE IN WATER HARVESTING SOILS [PDF]

open access: yesSociedade & Natureza, 2005
Dryland farming on Fuerteventura and Lanzarote (Canary Islands, Spain), which has an annual rainfall of less than 150 mm/year, has been based traditionally on water harvesting techniques (known locally as “gavias”). Periods of high productivity alternate
Díaz, F, Jiménez, C.C., Tejedor, M.
doaj  

WEPP model prediction evaluation of soil water content in northeast Uruguay

open access: yesAgrociencia, 2020
WEPP is a process-based model that estimates runoff and water erosion at slope level, maintaining a soil water balance at daily pace. The objective of this work is to adjust and validate the water balance component of the WEPP model in two watershed ...
Carlos Nicolás Blanco   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

PEMANFAATAN MATA AIR DUKUH BLAHKIUH UNTUK SISTEM PELAYANAN AIR TERINTEGRASI

open access: yesJurnal Sumber Daya Air
Spring water is one of the natural resources that are beneficial to human life such as fulfilling the needs of clean water, irrigation, and others. Non-integrated spring management has the potential to create conflicts among water users, as is the case ...
I Gusti Ngurah Kade Mahesa Adi Wardana   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy