Results 71 to 80 of about 1,440,241 (259)
Purpose: to develop the main stages of planning the measures of engineering and environmental protection of water bodies – drainage water inlets from irrigated lands. Materials and methods.
Tatyana I. Drovovozova +2 more
doaj +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Assessment of the ecological state of the water of Lake Malakhovo (Orenburg, Russia)
Background. Fresh surface water bodies are exposed to many anthropogenic and natural factors that can have a significant negative impact on the structure and functions of the entire ecosystem.
I.V. Shavrina +3 more
doaj +1 more source
New data characterizing the hydrophysical features (water temperature), water quality (water transparency, dissolved oxygen, and number of saprophytic bacteria), trophic status (chlorophyll a), and impact of the catchment (water color) of Lake Onego ...
Elena Tekanova +3 more
doaj +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
The traditions related to mining activities in the Silesia-Cracow area go back to the 11th century when lead, silver, and iron ores were exploited from open pit mines.
Pradela Alicja, Zygmuniak Andrzej
doaj +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source

