Results 111 to 120 of about 7,914,150 (283)

Retracted: Active Treatment of Water Chemistry for Swimming Pools Using Novel Automated System (NAS). [PDF]

Bioinorg Chem Appl, 2023
And Applications BC.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

An examination of the influence of drained peatlands on regional stream water chemistry. [PDF]

Hydrobiologia, 2023
Pschenyckyj C, Donahue T, Kelly-Quinn M, O'Driscoll C, Renou-Wilson F.   +4 more
europepmc   +1 more source

Water, water everywhere, and its remarkable chemistry

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2004
Photosystem II (PSII), the multisubunit pigment-protein complex localised in the thylakoid membranes of oxygenic photosynthetic organisms, uses light energy to drive a series of remarkable reactions leading to the oxidation of water. The products of this oxidation are dioxygen, which is released to the atmosphere, and reducing equivalents destined to ...
openaire   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Algal community response to water quality gradients across the wetlands in the Koshi Tappu Ramsar site, Nepal

Applied Phycology
Wetlands support diverse aquatic communities with algal assemblages serving as sensitive indicators of ecosystem health and environmental change. Algal abundance and diversity are shaped by complex interactions among physical, chemical, and biological ...
Susma Tamang, Binit Timalsina, Yadav Uprety, Shiva Kumar Rai, Ram Devi Tachamo-Shah, Deep Narayan Shah, Narayan Prasad Ghimire   +6 more
doaj   +1 more source

Lake water chemistry and population of origin interact to shape fecundity and growth in Daphnia ambigua. [PDF]

Ecol Evol, 2023
Rogalski MA, Ferah U.
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Diatom based transfer function for estimating the chemical composition of fossil water. Calibration based on salt lakes of the Lipez area in the southwestern Bolivian Altiplano.

Carnets de Géologie, 2002
Diatom assemblages and water chemistry were studied in 13 shallow salt lakes in the southern part of the Bolivian Altiplano. At each locality bottom sediment and water samples were collected simultaneously.
Roux Maurice, Risacher François, Servant-Vildary Simone   +2 more
doaj