Results 61 to 70 of about 2,317,337 (306)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

An Integrated Monitoring Approach to the Evaluation of the Environmental Impact of an Inshore Mariculture Plant (Mar Grande of Taranto, Ionian Sea)

Biology, 2022
The results of an ex-ante survey aiming to assess the impact of a fish farm in the Mar Grande of Taranto (southern Italy, Mediterranean Sea) on the surrounding environment are reported.
Adriana Giangrande, Margherita Licciano, Daniele Arduini, Jacopo Borghese, Cataldo Pierri, Roberta Trani, Caterina Longo, Antonella Petrocelli, Patrizia Ricci, Giorgio Alabiso, Rosa Anna Cavallo, Maria Immacolata Acquaviva, Marcella Narracci, Loredana Stabili   +13 more
doaj   +1 more source

European Multidisciplinary and Water-Column Observatory - European Research Infrastructure Consortium (EMSO ERIC): challenges and opportunities for strategic European marine sciences [PDF]

, 2016
EMSO (European Multidisciplinary Seafloor and water-column Observatory, www.emso-eu.org) is a large‐scale European Research Infrastructure I. It is a distributed infrastructure of strategically placed, deep‐sea seafloor and water column observatory ...
Beranzoli, Laura, Dañobeitia, Juan José, Faviali, Paolo, Gaughan, Paul, Huber, Robert, Llinás, Octavio, Lykousis, Vasilis, Miranda, Jorge M.A. de, O'Neill, Nick, Piera Fernández, Jaume, Radulescu, Vlad, Rolin, Jean-François, Ruhl, Henry A., Río Fernandez, Joaquín del, Terrinha, Pedro   +14 more
core  

Water depletion in the disk atmosphere of Herbig AeBe stars [PDF]

, 2011
We present high resolution (R = 100,000) L-band spectroscopy of 11 Herbig AeBe stars with circumstellar disks. The observations were obtained with the VLT/CRIRES to detect hot water and hydroxyl radical emission lines previously detected in disks around ...
Brittain, S., Dent, W. R. F., Fedele, D., Kamp, I., Pascucci, I., Thi, W. -F., Williams, J. P., Woitke, P.   +7 more
core   +6 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Analysis of Multi Temporal Satellite Imagery for Total Suspended Sediments in a Wave-Active Coastal Area-Gaza Strip Coastal Water, Palestine

International Journal of Environment and Geoinformatics, 2016
Sediment load materials is one of the key factors that determine the surface water quality, both of oceanic and river water, and it specifies water optical properties. Thus it provides a background for a plenty of applications and projects in the water
Midyan D.I. Aldabash, Füsun Balık Şanlı   +1 more
doaj   +1 more source

Mathematical models for an undisturbed soil-column [PDF]

, 2006
Some of the major industries of the Zebo region (China) include the petrochemical, pharmaceutical, china and ceramics sectors. Zibo is also abundant in natural resources.
Bohun, C. S.
core  

In situ analysis for intelligent control [PDF]

, 2007
We report a pilot study on in situ analysis of backscatter data for intelligent control of a scientific instrument on an Autonomous Underwater Vehicle (AUV) carried out at the Monterey Bay Aquarium Research Institute (MBARI).
Fox, M., Long, D., Py, F., Rajan, K., Ryan, J.   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The Vertical Metabolic Activity and Community Structure of Prokaryotes along Different Water Depths in the Kermadec and Diamantina Trenches

Microorganisms
Prokaryotes play a key role in particulate organic matter’s decomposition and remineralization processes in the vertical scale of seawater, and prokaryotes contribute to more than 70% of the estimated remineralization.
Hao Liu, Hongmei Jing
doaj   +1 more source