Results 51 to 60 of about 1,530,827 (359)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

National Water and Climate Center [PDF]

open access: yes, 2002
This branch of the National Resource Conservation Service (NRCS) leads the development and transfer of water and climate information and technology which support natural resources conservation.

core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Optimizing The Riparian Buffer: Harold Brook In The Skaneateles Lake Watershed, New York [PDF]

open access: yes, 2002
The use of riparian land buffers to protect water quality for human consumption and wildlife habitat has become an important conservation tool of both government and non-government agencies.
Jon M. Conrad   +2 more
core   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Assessing the mitigation effects of irrigation methods on a record-breaking drought: Crop Yield and Economic Loss in Shaanxi Province, China

open access: yesAgricultural Water Management
Drought events are intensifying under climate change, creating mounting risks for crop production and rural livelihoods in dryland regions. Shaanxi Province experienced a record drought in the 2025 agricultural season, reported as the most severe in the ...
Hao Chen   +10 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

The Effects of Biogeotextiles on the Stabilization of Roadside Slopes in Lithuania. [PDF]

open access: yes, 2006
Soil erosion, Water erosion, Soil conservation, Geotextiles, Geotextile mats, Roadside slopes, Vegetation cover, Biogeotextiles , Palm mat geotextiles - Borassus aethiopum - Mauritia flexuosa - Buriti mats - BORASSUS Project - LithuaniaBiogeotextiles ...
Booth, Colin A.   +3 more
core   +4 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

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