Results 41 to 50 of about 1,530,827 (359)

Our water resources and their conservation [PDF]

open access: yes, 1939
Life history, habits, structure, industry, conservation efforts for: Blue Crabs; Oyster; Fin fishes - shad, rock, croaker; Sport fish and fishing - marine and fresh-water; other aquatic forms - Diamondback terrapin, muskrat.
Truitt, R.V.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Velocity distribution and hydrodynamic characteristics of overland flow on biocrust-covered slopes

open access: yesInternational Soil and Water Conservation Research
Biological soil crusts (BSC), commonly distributed as ground cover in arid and semi-arid regions, are recognized for the significant role in regulating runoff yield processes.
Chenxi Dan   +7 more
doaj   +1 more source

Effect of windbreaks on wind speed reduction and soil protection against wind erosion

open access: yesSoil and Water Research, 2017
Windbreaks form efficient soil protection against wind erosion particularly at the time when soil cover is not protected by the cultivated plant vegetation cover. The objective of this research was to evaluate windbreaks efficiency in terms of wind speed
David ŘEHÁČEK   +4 more
doaj   +1 more source

Durability of biodegradable polymers for the conservation of cultural heritage [PDF]

open access: yes, 2019
The use of polymers for conservation of cultural heritage is related to the possibility to slow down or stop natural deterioration which, in many cases, corresponds to stopping the entrance of liquid water and to favor spontaneous water vapor removal ...
Botta L.   +5 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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