Results 101 to 110 of about 4,605,577 (336)

Constraining Upper Mantle Viscosity Using Temperature and Water Content Inferred from Seismic and Magnetotelluric Data [PDF]

, 2022
Florence Ramirez, Kate Selway, Clinton P. Conrad, Carolina Lithgow‐Bertelloni, Florence Ramirez   +4 more
openalex   +1 more source

Determination of water content using mass spectrometry [PDF]

, 1975
Mass spectrometer is used to measure small quantities of water present in different materials. System has been applied in measuring water and gases desorbed from microcircuitry insulation, can also be used with foods, polymeric materials, and organic ...
Hughes, D. B., Upchurch, B. T., Wood, G. M.   +2 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Land-use effects on soil-water retention characteristic [PDF]

, 2002
Tillage can negatively affect soil physical properties such as bulk density, organic matter content, and soil hydraulic properties, which in turn affect how plants grow. The objective of this study was to evaluate water retention characteristics of a Jay
Brye, Kristofor, Colton, Naomi
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Influência do teor de umidade na propriedade de tenacidade de espécies florestais

Floresta e Ambiente
A tenacidade da madeira é uma propriedade mecânica de interesse em situações em que o carregamento por impacto deve ser considerado, encontrando aplicação em silos, pontes e fôrmas para estruturas de concreto armado. Apesar das recomendações do Anexo B -
Denise Ortigosa Stolf, Marília da Silva Bertolini, Fabiane Salles Ferro, André Luis Christoforo, Francisco Antonio Rocco Lahr   +4 more
doaj   +1 more source

Water discharge and nutrient leaching from organic mixed crop rotation [PDF]

, 2006
Water discharge and nutrient leaching studies were conducted in an experimental field under organic farming practice for 20 years. The water discharge measurements cover five years out of a six-year crop rotation.
Kuisma, Miia, Seuri, Pentti
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Morpho-physiological responses of Lycium ruthenicum Murr. propagated by tissue culture to drought stress

Mongolian Journal of Biological Sciences
To estimate the drought tolerance of Lycium ruthenicum Murr., which is propagated through tissue culture, we conducted a laboratory experiment to investigate the morphological and physiological responses of this species under various levels of drought ...
Tsogtbaatar Urjinlkham, Dalaikhuu Usukhjargal, Tovuu Altanzaya, Jambalsuren Bayarmaa, Shagjjav Oyungerel   +4 more
doaj   +1 more source