Results 101 to 110 of about 4,441,068 (337)

The Impact of a Ski Piste on the Stock and Stoichiometry of Soil Carbon, Nitrogen, and Phosphorus: A Case Study on a Forest Area in Northeast China

open access: yesLand
The construction of sports spaces such as ski resorts leads to deforestation, soil degradation and carbon (C) loss. However, the impact of ski pistes on soil C and nutrients remains unclear.
Yongjie Han   +5 more
doaj   +1 more source

Gravimetric Soil Moisture Protocols [PDF]

open access: yes, 2003
The purpose of this resource is to measure soil water content by mass. Students collect soil samples with a trowel or auger and weigh them, dry them, and then weigh them again.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

In situ detection method of water content in newly poured concrete

open access: yesJournal of Intelligent Construction
Under environmental influence, newly poured concrete experiences excessive evaporation of surface water, which degrades concrete performance. Therefore, the water change process inside the concrete at construction sites needs to be monitored accurately ...
Wenbin Xu   +6 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Algae Biofuel Triacylglyceride Transesterification Optimization [PDF]

open access: yes, 2018
Algae biofuels may hold the key to solving the problem of fossil fuel consumption by being comparable in content, renewable, and carbon-neutral. Many biofuel researchers and corporations have undertaken to increase the production rate or capacity of ...
Ferenczy, Erik
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Experimental evaluation of new pipe sleeve with weep holes for concrete leakage prevention [PDF]

open access: yes, 2018
Mortar is a layer with high water absorption rate over concrete due to its porous structure. The mortar layer that frequently exposed to water or moisture is more likely to contain moisture in its layer.
Wan Nazri, Wan Muhammad Hafizuddin
core  

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