Results 81 to 90 of about 11,739,453 (240)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Water-related Legislation in the 2002 Virginia General Assembly

open access: yes, 2002
In 2002, the Virginia General Assembly convened on January 9 and adjourned on March 9, with a reconvened (“veto”) session on April 17. The legislature considered 2907 bills; 1587 were passed, 804 failed, and 517 were carried over to the 2003 session ...
Virginia Water Resources Research Center
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Compactação do solo e produção de cultivares de milho em latossolo vermelho: II - intervalo hídrico ótimo e sistema radicular Soil compaction and yield of corn hybrids in an oxisol: II - least limiting water range and root system

open access: yesRevista Brasileira de Ciência do Solo, 2009
Este trabalho teve como objetivo avaliar, no campo, a resposta de duas cultivares de milho em um Latossolo Vermelho, em seis níveis de compactação, quanto ao desenvolvimento do sistema radicular, bem como caracterizar a compactação do solo a partir do ...
Onã da Silva Freddi   +3 more
doaj   +1 more source

Report (Texas Water Development Board)

open access: yes, 2004
A guide on the practices, techniques, programs, and technologies that will protect water resources, reduce the consumption of water, reduce the loss or waste of water, improve the efficiency in the use of water, and increase the recycling and reuse of ...
Texas Water Development Board
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Other title: Kansas Municipal Water Conservation Plan Guidelines; Other title: Municipal Water Conservation Plan Guidelines

open access: yes, 2007
application/pdf; "August 2007.", "Prepared cooperatively by: Kansas Water Office, Kansas Department of Agriculture, Division of Water Resources, Kansas Department of Health & Environment, Division Of Environment, Bureau of Water, [and] Kansas Rural ...
Kansas Water Office.
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Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Influência do tipo de amostragem na constante dielétrica do solo e na calibração de sondas de TDR Influence of sampling type on the dielectric constant and calibration of TDR probes

open access: yesRevista Brasileira de Ciência do Solo, 2010
A técnica da TDR é uma importante ferramenta para o estudo do teor de água no solo. Para o correto emprego dessa técnica, é necessário calibrar modelos que relacionam o conteúdo volumétrico de água no solo com a constante dielétrica deste, considerando ...
Marcelo Rocha dos Santos   +2 more
doaj   +1 more source

Arizona department of water resources: Securing Arizona\u27s water future

open access: yes, 1998
The Arizona Department of Water Resources works to secure long-term dependable water supplies for Arizona\u27s communities. The Department: administers and enforces Arizona\u27s groundwater code, and surface water rights laws (except those related to ...
Arizona Department of Water Resources
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