Results 81 to 90 of about 15,661,404 (348)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Research on Electromagnetic Sensitivity Properties of Sodium Chloride during Microwave Heating

High Temperature Materials and Processes, 2020
The multimode resonant cavity is the most common cavity. The material often shows on selective heating performance during the heating process due to the effect of microwave heating having a closely relationship with the electromagnetism parameters.
Chen Hua, Chen Junjiang, Wang Weijun, Lin Huan   +3 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Physiological parameters formation of drought resistance in the process of adaptation of plants Ulmus pumila L. to adverse environmental factors in the conditions of the Astrakhan region

Siberian Journal of Life Sciences and Agriculture
Background.  The studies were carried out in the Astrakhan region, where dust storms are common and there is a deficit of precipitation. Only a few species of trees and shrubs can grow in this region, one of which is Ulmus pumila L.
Elena V. Kalmykova, Kristina A. Melnik, Anna I. Peredrienko   +2 more
doaj   +1 more source

Water Retention, Bulk Density, Particle Size, and Thermal and Hydraulic Conductivity of Arable Soils in Interior Alaska [PDF]

, 1990
The relative proportion of liquid, gas, and solid as constituents of soil depends on factors such as climate, biological activity, and management practices.
Sharratt, Brenton S.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Temporal dynamics of maize plant growth, water use, and leaf water content using automated high throughput RGB and hyperspectral imaging

Computers and Electronics in Agriculture, 2016
We conduct a greenhouse phenotyping study on two maize genotypes with two water regimes.Plant projected area accurately predicts shoot fresh weight, dry weight, and leaf area.Daily water consumption is derived and found to be determined by water ...
Y. Ge, Geng Bai, Vincent Stoerger, James c. Schnable   +3 more
semanticscholar   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Assessment of energy content indices for exploited small pelagic fish

Aquatic Living Resources
Energy content is a reliable indicator of an individual's body condition, influencing growth, reproduction, and survival with cascading effects on population dynamics and ecosystems through energy transfer.
Favreau Aurélien, Doray Mathieu, Spitz Jérôme, Huret Martin   +3 more
doaj   +1 more source