Results 101 to 110 of about 11,739,453 (240)
, 1968 One basin has been studied (Albion basin, Cassia County, Idaho) and the results published as an open file report by the Idaho Bureau of Mines and Geology.
Jones, Robert W.
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
SensorsSeveral medical techniques are based on the application of electromagnetic fields (EMFs) on the human body with therapeutic and/or diagnostic aims. The response of human tissues to the applied EMF is mediated by the tissues’ dielectric properties, which ...
Flavia Liporace +3 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Study on soil dielectric constant models: A review
Guan'gai paishui xuebao【Objective】 Soil dielectric constant measures the ability of a soil to transmit electric fields. It is the ratio of the capacitance of a soil sample to the capacitance of air-filled space of the same volume.
XU Xingqian +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Engineering ProceedingsA completely randomized design was used with four treatments including the control. The percentage of modified kepok banana starch substitution of the four treatments was 0%, 25%, 50%, and 75%, respectively of the total weight of wheat flour. Data of the
Rinanda Nur Arifah, Aan Sofyan
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Engineering ProceedingsStarch is composed of two types of carbohydrates, amylose and amylopectin. Improvements in the physical and chemical properties of natural starch can be made by modifying the starch. The modified starch has a healthy effect on the colon. The goal of this
Putri Eka Agustina Oprasita, Aan Sofyan
doaj +1 more source