Results 21 to 30 of about 1,518,821 (245)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Pulmonary Water Content in Critical Illness [PDF]

Anaesthesia and Intensive Care, 1976
Pulmonary extravascular water content was measured using a double indicator technique and results compared with chest radiography. It is concluded that careful chest radiography is an effective and simple technique for assessing the pulmonary extravascular water content.
A, Morton, P, Mahoney, W, Wilkie, J, McCosker, P, Hansen, J, Bowen, A B, Baker   +6 more
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Collapsible properties of Q2 loess and its collapsible prediction model

Shuiwen dizhi gongcheng dizhi
Long-term surface leakage caused by intermittent surface irrigation or project operation can lead to the humidification and settlement deformation of deep Q2 loess, compromising the safety of the structures.
Yukai FU, Guanglin LI, Tonglu LI, Ziran ZHANG, He LIU   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Experimental study on long-distance shear characteristics of fully weathered granite residual soil

Zhongguo dizhi zaihai yu fangzhi xuebao
In recent years, with the intensification of global climate change and human engineering activities, mass landslide events triggered by rainfall have become frequent in southeast China, posing serious threats to the lives and property safety of the ...
Wuwei MAO, Long PAN, Chenrui FENG, Xu MOU, Yinbing CUI, Zhen GUO, Yu HUANG   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Experimental Study on the Dynamic Compressive Response of Sand with Respect to Relative Density and Water Content

Medžiagotyra
This paper presents the findings of dynamic compression tests conducted on sand specimens utilizing a Æ 100 mm Split Hopkinson Pressure Bar (SHPB) apparatus. The study aims to investigate the dynamic response characteristics of sand with varying relative
Shuping SUN, Shu SUN, Qingxian YU, Yongchun LI, Xinwen QIAN   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Study on the Damage Characteristics of Red Sandstone Foundation Under Rainfall Infiltration in the Red-Bed Area of the Sichuan Basin—Taking Zhongjiang County as an Example

Buildings
The Sichuan Basin in China is one of the most concentrated areas of red beds in China. In the red-bed area, abundant rainfall can easily cause natural disasters, such as landslides, mudslides, collapses, and subsidence. This has had a great impact on the
Cong Yu, Wenwu Zhong, Xin Zhang, Tao Li, Zheng Fei   +4 more
doaj   +1 more source