Results 161 to 170 of about 5,516,205 (303)

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation. [PDF]

J Am Soc Nephrol, 2020
Dumas SJ, Meta E, Borri M, Goveia J, Rohlenova K, Conchinha NV, Falkenberg K, Teuwen LA, de Rooij L, Kalucka J, Chen R, Khan S, Taverna F, Lu W, Parys M, De Legher C, Vinckier S, Karakach TK, Schoonjans L, Lin L, Bolund L, Dewerchin M, Eelen G, Rabelink TJ, Li X, Luo Y, Carmeliet P.   +26 more
europepmc   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Metabolic Adaptation and Pulmonary ceRNA Network Plasticity in <i>Orientallactaga sibirica</i> During Water Deprivation Stress. [PDF]

Int J Mol Sci
Jin Y, Zhang R, Li X, Li L, Zhang D, Ling Y, Yuan S, Zhang X, Fu H, Wu X.   +9 more
europepmc   +1 more source

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

Advanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan   +5 more
wiley   +1 more source

Redefining Diagnostic Cut-Offs for the Indirect Water Deprivation Test. [PDF]

Clin Endocrinol (Oxf)
Akkara Y, Narula K, Lazarus K, Papadopoulou D, Choudhury S, Martin N, Meeran K.   +6 more
europepmc   +1 more source

Photo-Protective Mechanisms and the Role of Poly (ADP-Ribose) Polymerase Activity in a Facultative CAM Plant Exposed to Long-Term Water Deprivation. [PDF]

Plants (Basel), 2020
Vitale L, Vitale E, Costanzo G, De Maio A, Arena C.   +4 more
europepmc   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Dynamics of Pectins and Photosynthetic Traits in Sunflower and Tomato Subjected to Gradual Recoveries Preceded by Water Deprivation. [PDF]

Physiol Plant
Roig-Oliver M, Bresta P, Nikolopoulos D, Bota J, Flexas J.   +4 more
europepmc   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

Comparative Diagnostic Performance of Copeptin After Hypertonic Saline Infusion Versus Water Deprivation Test in Pediatric Patients with Polyuria-Polydipsia Syndrome. [PDF]

Int J Mol Sci
Ciortea DA, Petrea Cliveți CL, Vivisenco IC, Berbece SI, Gurău G, Matei MN, Nechita A.   +6 more
europepmc   +1 more source