Results 71 to 80 of about 337,947 (309)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Selected to survive and kill: Tityus serrulatus, the Brazilian yellow scorpion.

open access: yesPLoS ONE, 2019
Annually, more than 1.2 million scorpion stings and more than 3,000 deaths occur worldwide. Tityus serrulatus Lutz and Mello, 1922 (Scorpiones, Buthidae) is the most medically relevant species in Brazil where it is spreading rapidly and causing over 90 ...
Ricardo José Gonzaga Pimenta   +6 more
doaj   +1 more source

Effect of dehydration on the pharmacokinetics of oxytetracycline hydrochloride administered intravenously in goats (Capra hircus) [PDF]

open access: yes, 1998
1. The effects of various levels of dehydration induced by water deprivation were studied in six Nubian goats on the pharmacokinetics of oxytetracycline after intravenous administration (5 mg/kg). 2.
Abdullah, Abdul Salam   +3 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Episodes of water deprivation enhance daily hypertonic NaCl intake in rats

open access: yesBrazilian Journal of Medical and Biological Research, 2002
Water and 1.8% NaCl intake was recorded daily in adult male rats (N = 6) submitted to four water deprivations plus four sodium appetite tests, each at the end of each 7-day interval, or in controls (non-deprived, N = 6). Water deprivation was achieved by
D.T.B. Pereira   +3 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Root water conductivity of some herbaceous species. [PDF]

open access: yes, 2014
In this study, the values of water conductivity of roots are reported for eleven crops and grapevine. For some crops, two methods (pressure chamber and transpiration method) were compared.
FAGNANO, MASSIMO, RUGGIERO, CELESTINO
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Multi Dimensional Deprivation in India during and after the Reforms: Do the Household Expenditure and the Family Health Surveys Present Consistent Evidence? [PDF]

open access: yes
This paper uses the recent approach of multidimensional deprivation measures to provide a comprehensive and wide ranging assessment of changes to living standards in India during the period, 1992/93-2004/5.This covers the reforms and the immediate post ...
Ankita Mishra, Ranjan Ray
core  

No. 05: The Urban Food System of Bangalore, India [PDF]

open access: yes, 2017
Bangalore (officially Bangaluru) is one of India’s fastest-growing cities. It is now the fifth-largest urban agglomeration in India, and the capital and primate city of the state of Karnataka in terms of area, population and economic output.
Sami, Neha, Surie, Aditi
core   +1 more source

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