Results 91 to 100 of about 238,040 (312)
, 2007 The reliability assessment of water distribution systems is a complicated process. Manyresearchers have tried to devise methods to come up with indices that represent theperformance of water distribution networks.
Temam, R.A.
core
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Rehabilitation of a water distribution system using\ud sequential multiobjective optimization models
, 2015 Identification of the optimal rehabilitation plan for a large water distribution system (WDS) with a substantial number of decision\ud variables is a challenging task, especially when no supercomputer facilities are available.
Rahmani, F +3 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Detecting topological changes in large water distribution networks
, 2008 The issue of detecting topological changes in pipe networks due to failing pipes is an important one, especially when performing reliability analysis of a water distribution system.
Kapelan, Z. +2 more
core +1 more source
Multi-Model Prediction for Demand Forecast in Water Distribution Networks
Energies, 2018 This paper presents a multi-model predictor called Qualitative Multi-Model Predictor Plus (QMMP+) for demand forecast in water distribution networks. QMMP+ is based on the decomposition of the quantitative and qualitative information of the time-series ...
Rodrigo Lopez Farias +3 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Optimal design of isolation valve system for water distribution networks
, 2008 This paper presents a novel methodology for assessing an isolation valve system and the portions of a water distribution network (segments) directly isolated by valve closure. Planned (e.g. regular maintenance) and unplanned interruptions (e.g.
Savic, D., GIUSTOLISI, Orazio
core +1 more source
Parametric analysis for genetic algorithms handling parameters
Alexandria Engineering Journal, 2013 In the present paper, Evolutionary Algorithms (EAs) computing techniques have been used for economical studies that concern water distribution networks, such as, economical design of pipe network, parallel expansion, and pipe rehabilitation and ...
A.R. Ayad, H.A. Awad, A.A. Yassin
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source