Results 21 to 30 of about 5,256,229 (284)

Are fluoride levels in drinking water associated with hypothyroidism prevalence in England? A large observational study of GP practice data and fluoride levels in drinking water [PDF]

, 2015
Background While previous research has suggested that there is an association between fluoride ingestion and the incidence of hypothyroidism, few population level studies have been undertaken.
Spencer, S, Lowery, D., Lowery, D, Peckham, S, Spencer, S., Peckham, S.   +5 more
core   +2 more sources

External control of water fluoridation in a small municipality of northeast of Brazil

Revista de Odontologia da UNESP, 2020
Introduction Fluoridation of public water supply is an important measure in the prevention of dental caries. Objective This study aimed to monitor the fluoride (F) concentrations of a public water supply with water fluoridation program in a small ...
Maria Eliza Dantas BEZERRA, Thays Matias RIBEIRO, Franklin Delano Soares FORTE, Fábio Correia SAMPAIO, Jocianelle Maria Félix Fernandes NUNES   +4 more
doaj   +1 more source

Comparison of surface roughness of root cementum and orthodontically induced root resorption craters from high- and low-fluoridation areas: a 3D confocal microscopy study

Progress in Orthodontics, 2022
Background Fluoride has a major role in strengthening the structure of enamel against acids. Despite differences between caries and root resorption processes, both events inherently involve acidic dissolution of dental tissues.
Chelsea Mann, Lam L. Cheng, Sarbin Ranjitkar, Selma T. Elekdag-Turk, Tamer Turk, M. Ali Darendeliler   +5 more
doaj   +1 more source

Inequalities in public water supply fluoridation in Brazil: An ecological study

BMC Oral Health, 2008
Background The literature is scarce on the social and geographic inequalities in the access to and implementation of the fluoridation of public water supplies.
Moysés Simone T, Olandoski Marcia, da Silva Wander J, Gabardo Marilisa CL, Moysés Samuel J   +4 more
doaj   +1 more source

Contemporary multilevel analysis of the effectiveness of water fluoridation in Australia

Australian and New Zealand Journal of Public Health, 2015
Aims: Water fluoridation was extended in Queensland, Australia, across 2009–2011. A research program was commenced to inform the rationale for and the outcome of this program, to estimate the effectiveness of water fluoridation in preventing caries and ...
Loc Do, A. John Spencer
doaj   +1 more source

Water Professionals’ Opinions About Continuing Education on Water Fluoridation

Journal of the California Dental Association
Background This study assessed the interest of California water professionals in continuing education on water fluoridation and examined how this interest correlates with their roles, opinions on fluoridation’s oral health benefits, and the fluoridation ...
Evangelin Yeeda, Marjorie Stocks, Mark Bartson, Alfa Ibrahim Yansane, Susan A. Fisher-Owens, Howard Pollick   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Facts and Fallacies of the Fluoride Controversy: A Contemporary Perspective

International Dental Journal
Fluoride is a natural element recognized for its dental benefits. Fluoride prevents caries due to its antimicrobial activity, enhancing enamel resistance and promoting remineralization After decades of fluoridation of municipal water supplies to reduce ...
Lakshman Samaranayake, Thantrira Porntaveetus, James Tsoi, Nozimjon Tuygunov   +3 more
doaj   +1 more source