Results 31 to 40 of about 4,097 (252)

Coverage of fluoride data in water supply systems using the R software

Revista de Saúde Pública, 2022
OBJECTIVE To present a protocol to criticize data on fluoride monitoring in water with R software programming features, illustrating its application to describe data coverage, and fluoridation quality in 2015.
Camila de Moraes Paulino, Lorrayne Belotti, Moises Kim Zanotto de Azevedo, Paulo Frazão   +3 more
doaj   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Fluoridation in Chile: historical context, current programs, challenges, and future directions

Frontiers in Oral Health
As part of the Fluoride Across the World effort, this manuscript aims to examine the history, current programs, challenges, and future directions of fluoridation initiatives in Chile.
Rodrigo Mariño, Rodrigo Mariño, Rodrigo Mariño, Melisa Münzenmayer, Melisa Münzenmayer, Carlos Zaror, Carlos Zaror   +6 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Necessity of water fluoridation in Iran: A review on water fluoridation and prevention of dental caries

Journal of Oral Health and Oral Epidemiology, 2014
BACKGROUND AND AIM: Water fluoridation is one of the methods for prevention of dental caries. The purpose of this study was to review water fluoridation in the world and in Iran, and its effectiveness in reported literature.
Nathan Cochrane, Hamidreza Poureslami
doaj  

Fluoride in Natural Waters

, 2012
The element fluorine has long been recognised to have benefits for dental health: low-fluoride intake has been linked to development of dental caries and the use of fluoride toothpastes and mouthwashes is widely advocated in mitigating dental health problems.
Edmunds, W.M., Smedley, Pauline
openaire   +3 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Water fluoridation in 40 Brazilian cities: 7 year analysis

Journal of Applied Oral Science, 2013
Objectives Fluoride levels in the public water supplies of 40 Brazilian cities were analyzed and classified on the basis of risk/benefit balance. Material and Methods Samples were collected monthly over a seven-year period from three sites for each ...
Suzely Adas Saliba MOIMAZ, Nemre Adas SALIBA, Orlando SALIBA, Doris Hissako SUMIDA, Neila Paula de SOUZA, Fernando Yamamoto CHIBA, Clea Adas Saliba GARBIN   +6 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source