Results 31 to 40 of about 5,256,229 (284)

Situational diagnosis of policies in Latin American and Caribbean countries for the use of fluoride and reduction of sugar consumption

Brazilian Oral Research, 2023
Policy evaluation and guidance on fluoride use and sugar consumption in Latin American and Caribbean countries (LACC) may provide a scientific evidence basis for policymakers, dental professionals, civil society organizations and individuals committed to
Saul Martins PAIVA, Ivana Meyer PRADO, Matheus França PERAZZO, Carol C. GUARNIZO-HERREÑO, Ana Maria ACEVEDO, Jorge Luis CASTILLO, Ninoska ABREU-PLACERES, Rodrigo Andrés GIACAMAN, Antônio Pedro RICOMINI-FILHO, Stefania MARTIGNON, Zilson MALHEIROS, Bernal STEWART, Marcelo BÖNECKER   +12 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Potential fluoride toxicity from oral medicaments: A review [PDF]

Iranian Journal of Basic Medical Sciences, 2017
The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and ...
Rizwan Ullah, Muhammad Sohail Zafar, Nazish Shahani   +2 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Is water fluoridation correlated with hypothyroidism?

Journal of Education, Health and Sport, 2022
Introduction: Hypothyroidism is a global health problem. Primary thyroid hormone deficiency may be caused by a wide spectrum of health problems, e.g.
Piotr Michał Jarosz, Jakub Gołacki, Małgorzata Matuszek   +2 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Fluoridation in Chile: historical context, current programs, challenges, and future directions

Frontiers in Oral Health
As part of the Fluoride Across the World effort, this manuscript aims to examine the history, current programs, challenges, and future directions of fluoridation initiatives in Chile.
Rodrigo Mariño, Rodrigo Mariño, Rodrigo Mariño, Melisa Münzenmayer, Melisa Münzenmayer, Carlos Zaror, Carlos Zaror   +6 more
doaj   +1 more source

Feasibility of water fluoridation

The Journal of the American Dental Association, 1962
The Journal of the American Dental Association 65 (1962) 588-594. doi:10.14219/jada.archive.1962.0318 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:18:51 ; DOI:10.14219/jada.archive.1962.0318 ; Page Range: 588 ...
Research professor of chemistry and sanitary science, University of Florida Gainesville, Fla. ( host institution ), Black, A.P. ( author )   +1 more
openaire   +3 more sources