Results 131 to 140 of about 556,228 (310)

Water for People, Water for Life [PDF]

, 2002
This report documents the serious water crisis we are facing at the beginning of the 21st century. This crisis is one of water governance, essentially caused by the ways in which we mismanage water.

core  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Vernacular Knowledge and Water Management – Towards the Integration of Expert Science and Local Knowledge in Ontario, Canada

Water Alternatives, 2015
Complex environmental problems cannot be solved using expert science alone. Rather, these kinds of problems benefit from problem-solving processes that draw on 'vernacular' knowledge.
Hugh Simpson, Rob de Loë, Jean Andrey
doaj  

We must account for the results of water governance to deliver the SDGs and beyond

Environmental Research: Water
The crisis of water governance is one of results. This perspectives paper argues that we need to move beyond calling the global water crisis a crisis of governance.
Dustin Garrick, Gina Gilson, Rob Hope, Johannes Wagner, Graham Epstein, Elisha Ochieng Okoth, Fridah Silas   +6 more
doaj   +1 more source

Aligning local governance with SDGs: a study of local government systems in Pakistan

Development Studies Research
This study examines the experiences of local government councilors between 2013–2020 in four provinces of Pakistan. The study addresses three key questions: Firstly, it investigates the differences and commonalities in the local government structures ...
Abdur Rehman Cheema, Iftikhar Ahmad, Abid Mehmood   +2 more
doaj   +1 more source

Citizen participation dilemmas in water governance: An empirical case of Kumasi, Ghana. [PDF]

World Dev Perspect, 2020
Odei Erdiaw-Kwasie M, Abunyewah M, Edusei J, Buernor Alimo E.   +3 more
europepmc   +1 more source

Groundwater research and management: integrating science into management decisions. Proceedings of IWMI-ITP-NIH International Workshop on "Creating Synergy Between Groundwater Research and Management in South and Southeast Asia," Roorkee, India, 8-9 February 2005 [PDF]

Groundwater management / Governance / Groundwater development / Artificial recharge / Water quality / Aquifers / Groundwater irrigation / Water balance / Simulation models / Watershed management / Water harvesting / Decision making / South East Asia ...
Sharma, Bharat R., Sharma, K. D., Villholth Karen G.   +2 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Attitudes of political-administrative decision makers towards the implementation of nature-based solutions in water management – a case study on a hypothetical constructed wetland in the Tárcoles River basin

Ecosystems and People
Nature-based solutions (NBS) are actions that help communities address social-ecological challenges such as flooding and polluted groundwater. Nevertheless, research shows that in practice, NBS confront several barriers in planning and implementation ...
Franka Pätzke, Christoph Schulze, Jochen Hack, Karina Castro-Arce, Veronica Alejandra Neumann, Barbara Schröter   +5 more
doaj   +1 more source