Results 101 to 110 of about 172,262 (269)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Water Harvesting and Supplemental Irrigation for Improved Water Productivity of Dry Farming Systems in West Asia and North Africa [PDF]
, 2023 In the dry areas, water, not land, is the most limiting resource for improved agricultural production. Maximizing water productivity, and not yield per unit of land, is therefore a better strategy for dry farming systems.
Oweis, Theib
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Water Harvesting in Arid Lands [PDF]
, 1987 Paper Presented at the Kuwait Symposium on Management and Technology of Water Resources in Arid Zones, Kuwait, October 5-7, 1987.The use of water harvesting systems in arid lands offers the potential of making lands productive that are now largely ...
Cluff, C. Brent
core
Effects of aspen harvesting on groundwater recharge and water table dynamics in a subhumid climate [PDF]
, 2011 Numerical experiments were developed using different water table depths and soil textures to investigate the impact of aspen harvesting on hydrological processes on the Western Boreal Plain.
Devito, K.J. +4 more
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Water management and smallholder Fairtrade tea producers in South Western Uganda [PDF]
, 2007 Kayonza growers’ tea factory is a remote tea factory in south western Uganda which consists of two core estates and 4072 smallholder tea farmers currently producing tea over a total area of 1604 hectares.
Flowers, Cara
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Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Modelling of a roof runoff harvesting system: The use of rainwater for toilet flushing [PDF]
, 2011 The water balance of a four-people family rainwater harvesting system was calculated in a case study. The experimental water saving efficiency (WSE) was calculated as 87 %.
Sablayrolles, Caroline, +12 more
core +1 more source